Creating a New Class of Medicines: Eric Fischer on The Long Run

Today’s guest on The Long Run is Eric Fischer.

Eric is a professor at Dana Farber Cancer Institute in Boston. His structural biology and chemical biology expertise has led him down a path to become one of the world’s experts in an emerging category of medicine that includes targeted protein degraders and molecular glues.

These novel chemical entities can be made to interact with disease targets inside cells that traditional drugs – small molecule compounds and genetically engineered biologics – haven’t been effective against.

This is an exciting new frontier emerging at the nexus of structural biology, chemical biology, and drug discovery.

Eric was one of the key scientists, along with Nathanael Gray, who were tapped to lead a Center for Protein Degradation at Dana-Farber supported with $80 million from Deerfield Management, an investment firm, in 2018.

Some of this research has led to startup activity. Civetta Therapeutics and Neomorph are a couple of the companies Fischer has co-founded. 

This episode of The Long Run is sponsored by Dash Bio.

 

 

 

 

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Now, please enjoy this conversation with Eric Fischer on The Long Run.