23
Apr
2019
3 Lessons for Success in Research: Reflections from AACR 2019
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22
Apr
2019
The Gut Microbiome Modifies Immuno-Oncology Response, Suggesting Ways to Accelerate Activity
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18
Apr
2019
Life After Twitter
[Editor’s Note: David Shaywitz is a Palo Alto-based life science VC. He used to be active on Twitter. I asked him to share his reflections on leaving the platform–LT.] Quitting carbs last year was hard. Quitting Twitter this year has proved delightfully easy. You might even want to try it for yourself. Twitter has tremendous upside. Most notably, it provides...Read More
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16
Apr
2019
MIT Project ALPHA Aiming to Give Early Biopharma Investors Better Odds
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9
Apr
2019
The Road Less Traveled in Glycoscience: Carolyn Bertozzi on The Long Run
Today’s guest on The Long Run is Carolyn Bertozzi. She is a professor of chemistry at Stanford University, and an entrepreneur. Her research is focused on glycans – the beautiful and bewilderingly complicated sugar molecule structures attached to proteins. These carbohydrates are often underappreciated by biologists, and “orthogonal” to the way many think. But glycans are known to play a...Read More
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9
Apr
2019
Foundation, Flatiron Cross the Genotype-Phenotype Chasm, Show Clinical Cancer Genome Database at Work
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4
Apr
2019
The ABC’s (and D’s) of Changing Medicare Drug Policy
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1
Apr
2019
IFM Nails Second Big Deal, Selling NLRP3 Inhibitors to Novartis for $310M Upfront
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28
Mar
2019
Thermo Bets on Viral Vector Manufacturing, Precision & Genfit’s IPOs, & Not Much Else
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28
Mar
2019
Postmortem: 5 Lessons Learned from a Public Benefit Rare Disease Startup
On February 26, 2014 the first biotech public benefit corporation was born: Perlstein Lab PBC, which would eventually be renamed Perlara PBC. Almost exactly five years later, this bold and necessary — and some might say overly ambitious — experiment in rare disease drug discovery has ended. For now. Perlara, a company I founded that went on to raise $9.7...Read More
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26
Mar
2019
Life of a Scientific Entrepreneur: Bob Langer of MIT on The Long Run
Bob Langer is today’s guest on The Long Run. Langer, an Institute Professor at MIT, is one of the nation’s most accomplished scientists and scientific entrepreneurs. Much of his work has focused over the years on tissue engineering and drug delivery systems. It would take half this show to list all of Bob’s contributions to biotechnology, so I won’t. But...Read More
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25
Mar
2019
Researchers Look to the Immune System After Relentless Alzheimer’s Failures
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22
Mar
2019
Sage’s Depression Triumph, Biogen’s Alzheimer’s Defeat, & Apple Watch Hype
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18
Mar
2019
AI Drug Discovery Starts to Come of Age, as it Aims for the Clinic
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14
Mar
2019
Sharpless in the Saddle, NIH Threatened Again, & PBMs Prep for Senate Scrutiny
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12
Mar
2019
Seeing Lots of Single Cells, Up Close: Serge Saxonov of 10X Genomics on The Long Run
Serge Saxonov is today’s guest on The Long Run. Serge is the co-founder and CEO of Pleasanton, California based 10X Genomics. This privately held company, in a nutshell, is a fast-growing supplier for the genomics revolution. 10X, for those unfamiliar, makes instruments, chemical reagents for running experiments, and software that helps scientists collect and analyze various types of data. The...Read More
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7
Mar
2019
Gottlieb Exits, Biogen’s Big Gene Therapy Buy, and Lilly’s Pre-Emptive Price Cut
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6
Mar
2019
Beam Therapeutics, Pushing The Edges in Base Editing, Raises $135M
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5
Mar
2019
The Biotech Industry Can Help Address the Opioid Crisis. But We Aren’t Doing Enough
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1
Mar
2019
Pharma Dodges Senate Bullet, Roche Pays $4.8B for Spark, & BMS-Celgene Deal Wobbles
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