26
Jan
2023
VIR’s Scangos Retires, Pliant’s IPF Win, & Some Painful Decisions
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25
Jan
2023
Dimension Debuts with $350M to Back Startups at Bio & Tech Nexus
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24
Jan
2023
Biotech Needs to Get Back to Work in Person. Now.
Companies at the frontiers of science and medicine, developing new therapies for patients, are working on one of the most challenging endeavors known to humanity. Most would agree it’s more difficult than putting a man on the moon. The pandemic created a dramatic disruption to our globally networked economy. It will have far-ranging and long-lasting repercussions. It started with quarantine.... Read More
19
Jan
2023
From Computational Discovery to a New Psoriasis Drug: Jeb Keiper on The Long Run
Today’s guest on The Long Run is Jeb Keiper. Jeb is the CEO of Boston-based Nimbus Therapeutics. Nimbus made news in December 2022 when it sold its experimental Tyk2 inhibitor to Takeda Pharmaceuticals for $4 billion upfront and $2 billion in potential milestones. The drug’s value skyrocketed when it hit the primary endpoint of a Phase 2b clinical trial for... Read More
19
Jan
2023
Concert Gets Acquired, Structure Tees Up IPO, & a Proposed Noncompete Ban
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12
Jan
2023
JPM Vibes, Verily Cuts Back, & Eisai’s Transparent Price
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5
Jan
2023
J&J Walks Away from Fate, Century Cuts Back, & Moderna’s Strategic Buy
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5
Jan
2023
Oui Therapeutics: Shifting the Clinical, Societal and Business Impact of Suicide
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4
Jan
2023
Belharra Gets $130M from Versant, Genentech For Chemoproteomic Discovery
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3
Jan
2023
From Musician to Tech to Biotech Investor: D.A. Wallach on The Long Run
Today’s guest on The Long Run is D.A. Wallach. D.A. is the founder and general partner of Time BioVentures. Time BioVentures is a relative newcomer to the biotech world, investing out of a $100 million inaugural fund. The strategy is to invest in companies seeking to make a big impact in therapeutics, diagnostics, research tools, and healthcare delivery models. D.A.... Read More
21
Dec
2022
Madrigal’s NASH Persistence Pays, Gilead’s Mixed TIGIT Bag, & Zymeworks’ Rebound
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19
Dec
2022
A New Way to Treat Depression: Barry Greene on The Long Run
Today’s guest on The Long Run is Barry Greene. Barry is the CEO of Cambridge, Mass.-based Sage Therapeutics. Sage is developing a new medicine for the treatment of major depressive disorder and postpartum depression. Sage, and its partner, Biogen, recently completed a New Drug Application to the FDA for permission to start marketing zuranolone. The drug is a once-daily oral... Read More
15
Dec
2022
Amgen Buys Horizon, Mirati’s KRAS Drug OK, & Nimbus’s Tyk2 Windfall
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15
Dec
2022
Prescribing Cancer Drugs Off-Label is Tricky. Transparency and Standards Are Needed
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14
Dec
2022
Reprofiling ‘Drug Repurposing’
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10
Dec
2022
Sutro Delivers Complete Responses Against Deadly Pediatric Acute Myeloid Leukemia
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8
Dec
2022
Summit’s Bold Bid, Karuna’s Commercial Boss, & Gossamer’s Stumble
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4
Dec
2022
Hot Topics in Biopharma: Initial Impact of Digital, Data Dilemmas in Clinical Studies, and the Search for ‘New Normal’
For today: topics relevant to many drug developers (and others): The initial impact of digital The dilemma of data collection in early clinical studies The elusive search for “new normal” ways of working Initial impact of digital in biopharma The sexy promise of digital/data/AI in biopharma was that emerging digital technologies were going to solve our most important and vexing... Read More
1
Dec
2022
Alzheimer’s Debate, Nimbus to Challenge BMS, & a Microbiome First
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29
Nov
2022
Cajal Comes Out of Stealth with $96M for Alzheimer’s, Parkinson’s Drug Discovery
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