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16
May
2026

Can AI-Powered Consumer Health Break Medicine’s Destructive Spiral?

This week’s Duke-Margolis Health Policy Conference (video here) left me feeling there’s a remarkable opportunity to leverage technology to dramatically improve healthcare — and there’s almost no chance of it happening within the current healthcare system. A number of speakers (including UCSF’s Bob Wachter, my WSJ review of his recent book here) were genuinely enthusiastic about the transformative possibility of...
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9
May
2026

AI in Practice

AI is here – everywhere it seems.  How are we doing on translating this extraordinary promise into palpable value? Organizations As utopian AI “Accelerationists” have battled catastrophizing “Doomers” over competing visions of which eschaton is likely to be immanentized, a less visible but perhaps more consequential constituency has quietly focused on applying the still-evolving technology to the intractable problems of...
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21
Apr
2026

Small Molecule Synthesis Made Faster: Martin Burke on The Long Run

Martin Burke is today’s guest on The Long Run. Marty is a professor of chemistry, Director of the Molecule Maker Lab at the University of Illinois at Urbana-Champaign. He’s well known in the chemistry field for his pioneering work on blocc chemistry: iterative carbon-carbon bond formation that makes chemical synthesis faster, highly automated, and user-friendly. That was a big deal...
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14
Apr
2026

PhaseV Steps Up for Young Cancer Researchers

The Timmerman Traverse for Damon Runyon Cancer Research Foundation has a new major sponsor. PhaseV, the Boston-based company which provides AI/ML solutions to speed up and automate key aspects of clinical trials, has agreed to contribute $50,000 as the “Mt. Emerson” sponsor of this summer’s expedition in the High Sierras of California. This sponsorship could add up to much more....
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7
Apr
2026

Computation, Chemistry & Culture For Drug Discovery: Abbas Kazimi on The Long Run

Abbas Kazimi is today’s guest on The Long Run. Abbas is the CEO of Boston-based Nimbus Therapeutics. It’s a privately held company that discovers and develops oral small molecule drugs. It does this through a combination of computational chemistry, medicinal chemistry, AI, and the combined effort of a small group of talented and hardworking people. Nimbus is probably best known...
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4
Apr
2026

The Unreasonable Effectiveness of Lifestyle

It wasn’t quite like the dream where you’re standing in front of an audience and suddenly realize you’re not wearing pants, but at a recent Harvard Business School function, I felt a flush of affinity. The occasion was an annual event for students in the Harvard life sciences MS/MBA program, designed to recognize the hard work of students and faculty,...
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