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6
Jun
2026

Wellness Tech: Don’t Use as Directed

The Great Technology Plan for Wellness, to simplify only slightly, envisions a path to health that runs through data: collect more (through wearables and blood tests), analyze with AI, and deliver personalized coaching that improves as the data grow and the models sharpen. It sounds sensible, and one day it may even deliver — I’m long-term optimistic. But today it...
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24
May
2026

Summer Content Recommendations

Back by popular demand – my highly curated list of summer content recommendations for TR readers. Books Inside the Box – David Epstein By now, you’ve read, or should have read Range, David Epstein’s previous book and his paean to generalists (my reflections here). Now, he introduces us to an intriguing paradox – the unexpected power of constraints to inspire...
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16
May
2026

Can AI-Powered Consumer Health Break Medicine’s Destructive Spiral?

This week’s Duke-Margolis Health Policy Conference (video here) left me feeling there’s a remarkable opportunity to leverage technology to dramatically improve healthcare — and there’s almost no chance of it happening within the current healthcare system. A number of speakers (including UCSF’s Bob Wachter, my WSJ review of his recent book here) were genuinely enthusiastic about the transformative possibility of...
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9
May
2026

AI in Practice

AI is here – everywhere it seems.  How are we doing on translating this extraordinary promise into palpable value? Organizations As utopian AI “Accelerationists” have battled catastrophizing “Doomers” over competing visions of which eschaton is likely to be immanentized, a less visible but perhaps more consequential constituency has quietly focused on applying the still-evolving technology to the intractable problems of...
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21
Apr
2026

Small Molecule Synthesis Made Faster: Martin Burke on The Long Run

Martin Burke is today’s guest on The Long Run. Marty is a professor of chemistry, Director of the Molecule Maker Lab at the University of Illinois at Urbana-Champaign. He’s well known in the chemistry field for his pioneering work on blocc chemistry: iterative carbon-carbon bond formation that makes chemical synthesis faster, highly automated, and user-friendly. That was a big deal...
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