7
Feb
2024
Scion Starts with $310M to Build ‘Exceptional’ Biotech Startups
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1
Feb
2024
Vertex’s Next Big Thing, Regeneron’s Cell Therapy Play, & Takeda Bets on Protagonist
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25
Jan
2024
Sanofi Shells Out for Inhibrx, CG’s Breakout IPO, & a Cure for a Rare Deafness
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22
Jan
2024
Gene Expression In Therapeutic R&D: Rick Young on The Long Run
Today’s guest on The Long Run is Richard A. Young. Rick is a professor of biology at MIT and a core member of the Whitehead Institute dating back to its founding in the 1980s. Rick’s long and prolific research career has been dedicated to studying gene expression. He’s won a number of awards, and is a member of the National... Read More
18
Jan
2024
Arena Debuts with a Bang, Vertex Extends CRISPR, & BridgeBio Builds War Chest
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17
Jan
2024
One Thing Is Harder To Get From Investors Than Money: Candid Feedback
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11
Jan
2024
GSK Buys TSLP Antibody, J&J’s ADC Play, & Merck Adds Harpoon T-Cell Engagers
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9
Jan
2024
Investing in Healthy Aging: Jens Eckstein on The Long Run
Jens Eckstein is today’s guest on The Long Run. He’s an investment partner at Hevolution Foundation. It’s a Saudi Arabia-backed fund that supports basic research in healthy aging and invests in startups with partners to translate that science into interventions that help people live healthier, longer lives. These efforts are sometimes branded as increasing “healthspan” if not necessarily “lifespan.” Jens... Read More
8
Jan
2024
The Biopharma Industry Has a Data Integrity Problem
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4
Jan
2024
Karuna and RayzeBio Acquired, TCGX’s $1B Crossover Bet, & Cytokinetics’ Breakout
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4
Jan
2024
MOMA Gets Roche Deal, $66M Upfront, to Discover Novel Small Molecule Cancer Drugs
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2
Jan
2024
Rebooting AI in Drug Discovery on the Slope of Enlightenment
The past few years have seen a wave of AI investment in drug discovery in both large pharma companies and in venture-backed biotech startups. Expectations are running high. Management teams are betting that even marginal improvements on the ~90% failure rate of clinical trials will be worth the investment. While there have been hints of improved R&D metrics in... Read More
27
Dec
2023
Give to the Next Generation of Scientists
This is the time of year when many people sit down and think about the causes they want to support. I’m asking you to consider donating today to young scientists through the Damon Runyon Cancer Research Foundation. Why Young Scientists? Our system for funding science doesn’t do enough to support young people. The average age of a first-time NIH grant... Read More
26
Dec
2023
Bispecific Antibodies for Cancer: Shelley Force Aldred and Nathan Trinklein on The Long Run
Today, I have a dynamic duo of scientific entrepreneurs on the show – Shelley Force Aldred and Nathan Trinklein. They are the co-founders of San Francisco-based Rondo Therapeutics. The company raised $67 million in a Series A financing announced in March 2022. Shelley is the CEO and Nathan is the chief scientific officer. Rondo is developing bispecific T-cell engaging antibodies... Read More
21
Dec
2023
The Cultures of Large and Small Pharmas, plus: Can They Overcome The “Productivity Paradox” and Seize the AI Moment?
Spurred by several questions I’ve received from students and trainees, today’s year-end column examines some of the ways large biopharma companies are fundamentally different from small biotech companies and startups. We’ll also ask whether biopharma can overcome new technology’s dreaded “productivity paradox” and learn, quickly, how to apply AI to accelerate drug development. Large Pharmas vs Smaller Companies (Including Startups)... Read More
14
Dec
2023
Pfizer Closes Seagen, a Historic CRISPR Approval, & FTC Takes Shot at Sanofi
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13
Dec
2023
The Small Molecule Drug Discovery Renaissance: Jeff Jonker on The Long Run
Today’s guest is on The Long Run is Jeff Jonker. He’s the CEO of San Diego-based Belharra Therapeutics. It’s a startup that came out of stealth mode in January 2023 with a $50 million Series A financing from Versant Ventures, and a partnership with Genentech. I wrote about it at the time on TimmermanReport.com and am providing a link for... Read More
11
Dec
2023
11 Strategies for Motivating and Holding a Biotech Team Together for a Long Time
[This is an excerpt from The Biotech Leader’s Handbook by Angelos Georgakis.–LT.] The founder of Vertex Pharmaceuticals, Joshua Boger, once said, “Drug discovery is an insanely complicated activity; what makes a great leader in our industry is the ability to hold a team together for a very long time.” So, how can a leader in our industry hold a team... Read More
7
Dec
2023
AbbVie Buys Cerevel, Roche Buys Carmot, & Crowley Steps Into the Lion’s Den
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7
Dec
2023
Third Rock Joins F-Prime, Omega in $90M Round for ARTBIO’s Targeted Radiotherapies
Please subscribe and tell your friends why it’s worthwhile. Quality journalism costs money. When you subscribe to Timmerman Report at $199 per year, you reward quality independent biotech reporting, and encourage more. Subscribe Now Sign in to your account.