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16
Oct
2023

Catching Cancer Early, Investing in Data and AI: Jeff Huber on The Long Run

Today’s guest on The Long Run is Jeff Huber. He’s the co-founder and general partner at Triatomic Capital. It’s a relatively new venture fund that seeks to back “century-defining” businesses in Engineered Biology, New Materials, Next Gen Compute, New Energy, & Automated Economy. Jeff and his fellow partners are looking at startups that collect and analyze data to address big...
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5
Oct
2023

Fulfilling the Promise of Sickle Cell Gene Therapy

Two gene therapies for sickle cell disease, CRISPR/Vertex’s exa-cel and Bluebird Bio’s lovo-cel, are being reviewed by the FDA and are likely to win US approval for sale by the end of the year. While it will take more time to fully establish long-term safety and efficacy of these therapies, they offer a glimmer of hope for a cure. This...
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3
Oct
2023

Targeted Radiation for Cancer: Lori Lyons-Williams on The Long Run

Today’s guest on The Long Run is Lori Lyons-Williams. She’s the CEO of Menlo Park, Calif. and Vancouver, BC-based Abdera Therapeutics. Abdera is a startup developing targeted antibody drugs loaded with potent microdoses of radiation to give them extra tumor-killing punch. This type of treatment modality has been around for decades. Targeted radiation hasn’t lived up to the full potential...
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11
Sep
2023

Sterile Information: Early Forecasting Not The Answer To R&D Productivity Woes

Two recent Wall Street Journal deep-dives nicely bookend a critical, and unresolved, tension faced by large pharmaceutical companies: how can their R&D organizations discover, develop, and deliver the new medicines patients await, and the growth and return on investment that shareholders demand? Early this year, I discussed an April 2023 profile of Lilly by journalist Peter Loftus, who described how the company, led by a physician-scientist...
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5
Sep
2023

A Return to Kilimanjaro: Timmerman Traverse for Damon Runyon Cancer Research

Welcome to the next big biotech expedition — Timmerman Traverse for Damon Runyon Cancer Research Foundation. A team of executives, investors, and scientists are coming together on Kilimanjaro, the highest peak in Africa, in February 2024. We’re on a mission to raise $1 million for young scientists across the US. Damon Runyon gives promising young researchers the freedom to pursue...
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24
Aug
2023

How ‘Living Medicine’ Came to Be: Fred Appelbaum on The Long Run

Today’s guest is Fred Appelbaum. Fred is a physician, scientist, and administrator. He’s an executive vice president at the Fred Hutchinson Cancer Center in Seattle. He’s also the author of a new book, “Living Medicine: Don Thomas, Marrow Transplantation and the Cell Therapy Revolution” published by Mayo Clinic Press. It’s excellent. Fred knows a lot of this story from firsthand...
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