3
Dec
2019
Sticking With Epigenetics During Lean Times: Jigar Raythatha on The Long Run
Today’s guest on The Long Run is Jigar Raythatha. Jigar is the CEO of Cambridge, Mass.-based Constellation Pharmaceuticals. This company is built to develop drugs against epigenetic targets. Simply put, this is a way to turn genes on or off without altering the underlying DNA. The pharmaceutical industry fancied this idea about a decade ago, as a way to shut...Read More 
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2
Dec
2019
IFM, Staying Small, Raises (Merely) $55.5M, Promotes Former Novartis Exec to CEO
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26
Nov
2019
Tamping Down Inflammation & Synaptic Dysfunction in Alzheimer’s: John Alam on The Long Run
Today’s guest on The Long Run is John Alam. John is the co-founder and CEO of Cambridge, Mass.-based EIP Pharma. This is a small company running clinical trials to test an unconventional idea for the treatment of Alzheimer’s. The gist is that if you can tamp down certain kinds of inflammation, you might be able to stop some of the...Read More
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14
Nov
2019
Merck’s Ebola Vaccine Triumph, Weill’s $106M Neurohub & Teva’s Reversal
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12
Nov
2019
Scientist, Entrepreneur, Rock Collector: Tim Springer on The Long Run
Today’s guest on The Long Run is Tim Springer. Tim wears many hats. First and foremost, he’s a scientist. An immunologist to be specific, at Harvard Medical School. He’s best known for his discovery of integrins, a class of transmembrane receptors. Now in his early 70s, Tim recently won the Gairdner Award, sometimes called the Canadian Nobel. The prize committee...Read More
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7
Nov
2019
Takeda’s Busy Week, Halozyme’s Stumble, and New FDA Commish On Deck
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31
Oct
2019
Amgen’s Bet on BeiGene, David Hung’s Megaround, & Zolgensma Speed Bump
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29
Oct
2019
The Story of Henri Termeer: John Hawkins and Jim Geraghty on The Long Run
Today’s guests on The Long Run are John Hawkins and Jim Geraghty. John is a biotech industry veteran and the vice chairman of Odgers Berndtson, an executive recruiting firm in New York. He’s also the author of the new biography on Henri Termeer, the longtime CEO of Genzyme and one of the founding fathers of the biotech industry. Jim Geraghty...Read More
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24
Oct
2019
Vertex’s Watershed for CF, Biogen’s Head-Scratcher, and Seattle Genetics Nails HER2Climb
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17
Oct
2019
Reata Booms, Alexion Buys Achillion, & Teva Drops the Ball (Big Time)
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15
Oct
2019
Turning Synthetic Biology Into ‘Living Drugs’: Synlogic’s Aoife Brennan on The Long Run
Today’s guest on The Long Run is Aoife Brennan. Aoife (it’s pronounced EE-fuh in her native Ireland) is the CEO of Synlogic Therapeutics. The company, based in Cambridge, Mass., is trying to build on years of work at MIT in synthetic biology. The basic idea is to create what the company calls Synthetic Biotics, or what you can call “Living...Read More
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10
Oct
2019
UCB’s $2B Bet on Rare Disease, BioNTech’s IPO Haircut, & Greenwood Eases Out the Door
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9
Oct
2019
12 VCs Who Matter, But You Hardly Ever Read About
This article was first published on November 20, 2017, then revised and updated October 9, 2019 Vinod Khosla, the tech venture capitalist, has said 95 percent of VCs add zero value to a startup other than cash. About four out of every five VCs, he said, actually damage their own investments with bad advice. When asked to apply the Khosla test...Read More
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8
Oct
2019
Join Me and a Biotech Team on the Trek of a Lifetime for Cancer Research
Earlier this year, I led a team of 27 biotech professionals to Mt. Kilimanjaro, the highest peak in Africa. Each of us committed to raise $50,000 for cancer research at Fred Hutch. We ended up raising $1.6 million. We had an amazing time together. We all made it to the top. I want to do it again. This time we’re...Read More
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3
Oct
2019
ESMO Wrap, A Twitchy IPO Market, & Novartis Picks Microsoft for AI Help
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1
Oct
2019
From Farm Field to MIT Lab: Phil Sharp on The Long Run
Today’s guest on The Long Run is Phil Sharp. Phil is one of the world’s most influential biologists and scientific entrepreneurs. Phil won the Nobel Prize in 1993 for his work on RNA splicing. Back in the 1970s in his MIT lab, he looked at the basics of RNA splicing. That paved the way for the discovery of “discontinuous genes.”...Read More
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26
Sep
2019
Big IPO Week On Deck, Amazon & Walmart Health Moves, & Akcea Exec Shakeup
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19
Sep
2019
Speaker Pelosi’s Envisioned Drug Price Clampdown, Lundbeck’s Move into Migraine, & Diabetes Drug-Device Pairings
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17
Sep
2019
A Nonprofit That Carried a TB Drug Through the FDA: Bruce Carter on The Long Run
Today’s guest on The Long Run is Bruce Carter. Bruce is the chairman of the board at the New York-based TB Alliance. He’s a senior statesman of the industry, known for his run as CEO of Seattle-based ZymoGenetics, and for serving on a variety of boards. He’s the chairman of the board at Watertown, Mass.-based Enanta Pharmaceuticals, the developer of...Read More
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12
Sep
2019
10X Pops on IPO Day, Amgen’s KRAS Drug Tantalizes, & Lilly’s RET Drug Impresses
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