15
Aug
2019
Roche/Genentech’s Clever NTRK Strategy, Regeneron’s Ebola Win & PCR Pioneer Passes
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8
Aug
2019
Novartis’ No-No, Bayer Buys BlueRock, and Job Switches Galore
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8
Aug
2019
From Pharma VC to Cell Therapy Startup: Janelle Anderson on The Long Run
Today’s guest on The Long Run is Janelle Anderson. Janelle is the chief strategy officer of Century Therapeutics. This is a company using induced pluripotent stem cells to make off-the-shelf cell therapies for cancer. This is the new dream of cell therapy, as scientists imagine ways to lower the cost and expand access for patients following the first wave of...Read More
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11
Jul
2019
Better Cancer Treatment Through Better Information: Cindy Perettie on The Long Run
Today’s guest on The Long Run is Cindy Perettie. Cindy is the CEO of Cambridge, Mass.-based Foundation Medicine. This company does genomic analysis on tumors. If you know more of this molecular nitty-gritty information – things like the underlying gene mutations that send cancer cells into out-of-control growth sprees – then you ought to occasionally come up with more effective...Read More
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11
Jul
2019
BioNTech Snags $320m, Roche/Spark Delay, & Summer Job Switches
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2
Jul
2019
Cancer Survivor and Cancer Drug Developer: Laura Shawver on The Long Run
Today’s guest on The Long Run is Laura Shawver. Laura is the CEO of San Diego-based Synthorx. This company, based on research from The Scripps Research Institute, is using a couple of newly invented base pairs of DNA to make site-specific modifications on fully expressed proteins. This capability, Synthorx believes, could be put to practical use to craft ideal drug-like...Read More
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27
Jun
2019
AbbVie & Allergan (Groan), Adaptive Headlines IPO Rush, & FDA Cops on the Beat
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20
Jun
2019
Pfizer’s Wager on Small Molecules, Summer IPO Flurries, Gilead’s Protein Degrader Play
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13
Jun
2019
Who Will Be the Next Celgene of Dealmaking?
Stars aligned beautifully, not long ago, for dealmaking at Celgene. The company, early this decade, was raking in the dough from the multiple myeloma drug Revlimid. Cash had to be spent somewhere. Celgene didn’t have much of its own R&D. Shareholders weren’t clamoring for their cut, via quarterly cash dividends. The stock soared, without any jet fueled-share buybacks. Letting cash...Read More
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13
Jun
2019
Predicting Who Will Benefit from Cancer Drugs: Liz O’Day on The Long Run
Today’s guest on The Long Run is Liz O’Day. Liz is the founder and CEO of Cambridge, Mass.-based Olaris Therapeutics. This is a scrappy little startup that’s studying metabolites that could provide clues for predicting which patients are most likely to respond to certain cancer drugs. Figuring out which patients are likely to respond is one of those perennial challenges...Read More
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30
May
2019
Third Rock and Friends Bet $110M On Thrive, a Hopkins-Inspired Cancer Screening Startup
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22
May
2019
From Open Biology to Pharma Leadership: Jay Bradner of Novartis on The Long Run
Today’s guest on The Long Run is Jay Bradner. Jay is the president of the Novartis Institutes for Biomedical Research (NIBR). This is one of the heavyweight organizations in Big Pharma industry R&D. When Novartis planted this operation in the heart of Cambridge, Mass. more than a decade ago, it was the start of a trend toward Big Pharma R&D...Read More
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16
May
2019
Amgen Swings for the RAS Fence, Gilead’s Grilling on Price, & Agios Enlarges the Pie
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8
May
2019
An Elephant for Immunology Drugs: Sheila Gujrathi on The Long Run
Today’s guest on The Long Run is Sheila Gujrathi. Sheila is the CEO of San Diego-based Gossamer Bio. This immunology drug developer is an example of what I’ve lately started calling an “elephant” startup (see February TR coverage of Maze Therapeutics for another example). Gossamer was co-founded by Sheila and Faheem Hasnain. They were the dynamic duo that led Receptos...Read More
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8
May
2019
Thank You, Biotech: Kili Climb to Fight Has Crushed Its $1m Goal for Cancer Research
Today, I want to say thank you. Thank you to the biotech community for your Incredibly Generous support of the Kilimanjaro Climb to Fight Cancer. You have enabled us to reach our goal of raising $1 million this year for lifesaving cancer research at Fred Hutch. Who are we? We are a team of 28 biotech executives and investors. 14...Read More
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23
Apr
2019
Blazing a New Trail in Psychiatry & Women’s Health: Jeff Jonas on The Long Run
Today’s guest on The Long Run is Jeff Jonas. Jeff is the CEO of Cambridge, Mass.-based Sage Therapeutics. The company made big news – front page of the New York Times – a month ago. That’s when it won FDA clearance to sell the first drug ever for postpartum depression. It’s a big story for a number of reasons. Postpartum...Read More
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9
Apr
2019
The Road Less Traveled in Glycoscience: Carolyn Bertozzi on The Long Run
Today’s guest on The Long Run is Carolyn Bertozzi. She is a professor of chemistry at Stanford University, and an entrepreneur. Her research is focused on glycans – the beautiful and bewilderingly complicated sugar molecule structures attached to proteins. These carbohydrates are often underappreciated by biologists, and “orthogonal” to the way many think. But glycans are known to play a...Read More
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9
Apr
2019
Foundation, Flatiron Cross the Genotype-Phenotype Chasm, Show Clinical Cancer Genome Database at Work
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1
Apr
2019
IFM Nails Second Big Deal, Selling NLRP3 Inhibitors to Novartis for $310M Upfront
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28
Mar
2019
Thermo Bets on Viral Vector Manufacturing, Precision & Genfit’s IPOs, & Not Much Else
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