22
Apr
2025
The Four Dysfunctions of Corporate Cultures—Applied to Biopharma
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26
Feb
2025
How to Know when a Company Should Throw in the Towel
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20
Nov
2024
US-China Partnership: Just Hitting its Stride, and Now Threatened
Curon, Chimagen, Hengrui, LaNova…the list goes on of Chinese biotech companies that have recently licensed potential blockbuster drug candidates for cancer, autoimmunity and more to US pharma and biotech companies for further development. Over the past year or so, there has been a dramatic increase in both the number of deals to obtain rights to assets discovered in China, and... Read More
15
Oct
2024
Money Is Coming Back To Biotech. Don’t Spend It All At Once
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8
Jan
2024
The Biopharma Industry Has a Data Integrity Problem
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21
Nov
2023
Nimble Pharmas and Plodding Biotechs: Responses to the IRA Have Flipped the Script
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27
Jun
2023
Biopharma Has a Primary Care Problem
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19
Apr
2023
The “D” Word: Delivery is the Next Frontier for Genetic Medicines
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10
Feb
2023
Why Is It So Hard to Get Patients the Medicines They Need?
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12
Oct
2022
Inflation Reduction Act: Big Changes Lurking for Drug Development
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7
Sep
2022
Seek Truth and Kill Quickly: Learning the Hard Way About Biotech Startups
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7
Jun
2022
Lessons from the Road: What I Learned from Remix’s Series B
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11
May
2022
The Limits of Biomedical Innovation, and Why We Should Embrace Them
Last October, I wrote for this publication about the emergence of Antibody-Drug Conjugates (ADCs) for cancer, based on my father’s experience being treated with Padcev for bladder cancer. A few months later, I posted on Twitter that, while Padcev had stopped working for my father, he had since started on another ADC called Trodelvy. His tumors had shrunk. He was... Read More
7
Mar
2022
The Globally Integrated Biotech Is Down, But Not Out
“What else can you do? The entire isolation of Russia. Nowadays we see real solidarity of the whole world to cancel or stop any economic, cultural, technological, financial connections with Russia and we urge the same from the Drug Discovery community.” This was the message on Mar. 5 from Andrey Tolmachov, founder and CEO of Enamine Ltd., a Ukrainian chemistry... Read More
9
Feb
2022
Going Private: The Public Bear Market Will Soon Hit Private Companies
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3
Jan
2022
The Future is Simple: How the Genetic Revolution is Making Old Modalities Stronger
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30
Dec
2021
A Doctor’s View From the Front Line of the Omicron Wave
My phone buzzed with alerts about record-setting case numbers as I rushed between patients. A pile of tiny bottles with swabs floating in pink liquid accumulated while awaiting PCR testing. Patients with coughs and sniffles lined up outside the door, waiting to be seen. My shift as an internal medicine physician yesterday in MGH Chelsea’s urgent care facility reminded me... Read More
20
Oct
2021
ADCs: If at First You Don’t Succeed…
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12
Aug
2021
Is EQRx an Existential Threat to the Biopharma Industry?
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12
Jul
2021
One-and-Done Gene Editing: A Feature or Flaw?
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