31
Mar
2026
Inspired by Mother Nature, Discovering New Drugs: Viswa Colluru on The Long Run
Viswa Colluru is today’s guest on The Long Run. Viswa is the founder and CEO of Boulder, Colo.-based Enveda. The startup company, founded in 2019, is focused on discovering and developing small molecule drugs with novel mechanisms of action. It relies on a chemistry-based approach to drug discovery, drawing inspiration from products found in nature. The privately held company has... Read More
17
Mar
2026
Europe’s Biotech Investment Crisis: Otello Stampacchia on The Long Run
Otello Stampacchia is today’s guest on The Long Run. Otello is the founder and managing director of Omega Funds. It’s a transatlantic biotech venture firm with offices in Boston and Geneva, Switzerland. He’s a native of Italy and you might say a true international businessman, deeply rooted in the issues startups face in various geographies around the world. This conversation... Read More
3
Mar
2026
T-cell Engagers for Autoimmune Disease: Ken Song on The Long Run
Ken Song is today’s guest on The Long Run. First things first, this episode was recorded before news broke that Candid Therapeutics went public via a reverse merger with RallyBio. But I must say, that deal was no surprise. Ken was on The Long Run five years ago, in November 2021. At that time, he was CEO of San Diego-based... Read More
17
Feb
2026
Discovering Drugs for Cancer and Autoimmunity: Ansu Satpathy
Ansu Satpathy is today’s guest on The Long Run. Ansu is a physician-scientist and an associate professor of pathology and immunology at Stanford University. He’s co-director of the Parker Institute for Cancer Immunotherapy Center at Stanford Medicine, and the co-founder of several startup companies. These include Cartography Biosciences (a cancer drug developer), Santa Ana Bio (a developer of precision autoimmune... Read More
22
Jan
2026
Helping People Lose Weight and Live Healthy: Ron Renaud on The Long Run
Ron Renaud is today’s guest on The Long Run. He is the CEO of Waltham, Mass.-based Kailera Therapeutics. Kailera is pursuing what could be the biggest opportunity in pharmaceutical industry history. It’s developing a portfolio of GLP-1-based drugs for obesity. Drugs in this category have been around a long time for treatment of Type 2 diabetes, but over the last... Read More
8
Jan
2026
Following the Science to Immunology: Kate Haviland on The Long Run
Kate Haviland is today’s guest on The Long Run. Kate is the former CEO of Cambridge, Mass.-based Blueprint Medicines. Blueprint was one of the big biotech success stories of 2025. The company was acquired by Sanofi for $9.1 billion in cash at closing, and potentially $9.5 billion if certain milestones are met. The company started out with a vision for... Read More
15
Dec
2025
Small Molecules to Correct a Rare Kidney Disease: Emily Conley on The Long Run
Emily Conley is today’s guest on The Long Run. She is the CEO of Berkeley, Calif.-based Renasant Bio. The big idea at Renasant is to develop oral small molecule drugs to treat patients with autosomal dominant polycystic kidney disease, known as ADPKD. Patients with this disease develop cysts on their kidneys that sometimes cause the kidney to balloon in size... Read More
20
Nov
2025
Building a Rare Disease Company: Neil Kumar on The Long Run
Neil Kumar is today’s guest on The Long Run. Neil is the founder and CEO of Palo Alto, Calif.-based BridgeBio Pharma. BridgeBio got started a little more than 10 years ago with an idea of creating what it calls a “hub and spoke” business model for rare disease drug development. The hope was to find opportunities that were biologically compelling,... Read More
12
Nov
2025
Reinventing Drug Discovery with AI: Marc Tessier-Lavigne on The Long Run
Marc Tessier-Lavigne is today’s guest on The Long Run. Marc is the chairman and CEO of South San Francisco-based Xaira Therapeutics. Xaira is using computers to design protein drugs from scratch, building on work from co-founder David Baker’s lab at the University of Washington. Designing protein drugs on computers with ideal properties is a plenty big idea that won Baker... Read More
28
Oct
2025
Innate Immune System Activators for Cancer: Art Krieg on The Long Run
Art Krieg is today’s guest on The Long Run. Art is the founder and CEO of a Cambridge, Mass.-based startup called Zola Therapeutics. Zola is developing an oligonucleotide drug candidate to activate a family of Toll-like receptors known as TLR7 TLR8 and TLR9. Activating these receptors is thought to spur the innate immune system to attack cancer cells. Art designed... Read More
14
Oct
2025
Creating a New Class of Medicines: Eric Fischer on The Long Run
Today’s guest on The Long Run is Eric Fischer. Eric is a professor at Dana Farber Cancer Institute in Boston. His structural biology and chemical biology expertise has led him down a path to become one of the world’s experts in an emerging category of medicine that includes targeted protein degraders and molecular glues. These novel chemical entities can be... Read More
29
Sep
2025
A Song of Science and Hope: Bruce Levine & Mags McCarthy on The Long Run
Today’s guests on The Long Run are Bruce Levine and Mags McCarthy. Bruce is a scientist at the University of Pennsylvania Perelman School of Medicine. He’s one of the world leaders in engineering CAR-T cell therapies for cancer. Mags McCarthy is a country music star. What do these two have in common? A shared desire to sing from the rooftops... Read More
17
Sep
2025
Predicting Leukemia Risk At Scale: Dr. Lachelle Weeks on The Long Run
Dr. Lachelle Weeks is today’s guest on The Long Run. Lachelle is a physician-scientist in the adult leukemia program at Dana-Farber Cancer Institute in Boston. She treats patients who have precursors to myeloid cancers such as acute myeloid leukemia. Her research is looking at ways to detect the early warning signs of blood cancer early, when these malignancies are most... Read More
28
Aug
2025
Creating Lower Cost, Accessible Cell & Gene Therapies: Jen Adair on The Long Run
Jen Adair is today’s guest on The Long Run. Jen is a professor and Vice Chair in the Department of Genetic and Cellular Medicine, and Associate Director of the Horae Gene Therapy Center at the University of Massachusetts Chan Medical School. Her laboratory develops tools and methods for safe and effective delivery of gene therapy. In this conversation, you’ll hear... Read More
6
Aug
2025
CAR-T Cells Against Solid Tumors: Sabah Oney on The Long Run
Sabah Oney is today’s guest on The Long Run. Sabah is the CEO of Philadelphia and San Francisco-based Dispatch Biotherapeutics. This startup is developing engineered CAR-T cell therapies for solid tumors. The goal is to bring the power of CAR-T cell cures to a wider group of patients, beyond those with blood cancers. Dispatch was founded by some of the... Read More
23
Jul
2025
Creative Ways to Back Young Scientists: Andy Rachleff and Yung Lie on The Long Run
Yung Lie and Andy Rachleff are today’s guests on The Long Run. Yung is the president and CEO of the Damon Runyon Cancer Research Foundation, based in New York. Andy is the board chair. Andy was one of the founding partners of Benchmark Capital, the prominent Silicon Valley VC firm, and today is the chairman of Wealthfront. This is a... Read More
1
Jul
2025
A Two-Pronged Attack on Cancer: Claire Mazumdar on The Long Run
Claire Mazumdar is today’s guest on The Long Run. She is the founding CEO of Boston-based Bicara Therapeutics. Bicara is developing a bifunctional antibody for head and neck cancer. It’s called ficerafusp alfa, and it’s designed to bind with a couple of well-known biological targets, EGFR and TGF-beta. The idea is to block a well-known cancer driver in EGFR, while... Read More
11
Jun
2025
Finding Therapies in Long Non-Coding RNA: John Rinn on The Long Run
John Rinn is today’s guest on The Long Run. John is the Leslie Orgel and Marvin Caruthers professor of RNA science at the University of Colorado in Boulder. His research is focused on long non-coding RNAs. This is the vast expanse of the genome that doesn’t contain genes with code for making proteins. Researchers once dismissed this area of the... Read More
28
May
2025
A New and Old Idea for Cardiovascular Disease & Diabetes: Ethan Weiss & Josh Lehrer on The Long Run
Ethan Weiss and Josh Lehrer are today’s guests on The Long Run. Ethan is the co-founder and chief scientific officer of South San Francisco-based Marea Biosciences. Josh is the CEO. They are seeking to blaze a new trail with a drug to reduce the risk of cardiovascular disease and type 2 diabetes. It’s a monoclonal antibody aimed at ANGPTL4. There... Read More
13
May
2025
Biologic Drug Discovery Made Faster: Peyton Greenside on The Long Run
Peyton Greenside is today’s guest on The Long Run. Peyton is the co-founder and CEO of San Mateo, Calif.-based BigHat Biosciences. The company was started in 2019 to build on advances in synthetic biology and machine learning to design antibody drugs with a variety of different properties, faster. The company has gone on to raise more than $100 million in... Read More