Tag

The Long Run

11
Jul
2019

Better Cancer Treatment Through Better Information: Cindy Perettie on The Long Run

Today’s guest on The Long Run is Cindy Perettie. Cindy is the CEO of Cambridge, Mass.-based Foundation Medicine. This company does genomic analysis on tumors. If you know more of this molecular nitty-gritty information – things like the underlying gene mutations that send cancer cells into out-of-control growth sprees – then you ought to occasionally come up with more effective...
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2
Jul
2019

Cancer Survivor and Cancer Drug Developer: Laura Shawver on The Long Run

Today’s guest on The Long Run is Laura Shawver. Laura is the CEO of San Diego-based Synthorx. This company, based on research from The Scripps Research Institute, is using a couple of newly invented base pairs of DNA to make site-specific modifications on fully expressed proteins. This capability, Synthorx believes, could be put to practical use to craft ideal drug-like...
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13
Jun
2019

Predicting Who Will Benefit from Cancer Drugs: Liz O’Day on The Long Run

Today’s guest on The Long Run is Liz O’Day. Liz is the founder and CEO of Cambridge, Mass.-based Olaris Therapeutics. This is a scrappy little startup that’s studying metabolites that could provide clues for predicting which patients are most likely to respond to certain cancer drugs. Figuring out which patients are likely to respond is one of those perennial challenges...
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8
May
2019

An Elephant for Immunology Drugs: Sheila Gujrathi on The Long Run

Today’s guest on The Long Run is Sheila Gujrathi. Sheila is the CEO of San Diego-based Gossamer Bio. This immunology drug developer is an example of what I’ve lately started calling an “elephant” startup (see February TR coverage of Maze Therapeutics for another example). Gossamer was co-founded by Sheila and Faheem Hasnain. They were the dynamic duo that led Receptos...
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9
Apr
2019

The Road Less Traveled in Glycoscience: Carolyn Bertozzi on The Long Run

Today’s guest on The Long Run is Carolyn Bertozzi. She is a professor of chemistry at Stanford University, and an entrepreneur. Her research is focused on glycans – the beautiful and bewilderingly complicated sugar molecule structures attached to proteins. These carbohydrates are often underappreciated by biologists, and “orthogonal” to the way many think. But glycans are known to play a...
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27
Feb
2019

Staying Resilient, Finding a Way Forward: Julia Owens on The Long Run

Julia Owens is today’s guest on The Long Run. Owens is the CEO of Ann Arbor, Michigan-based Millendo Therapeutics. This company develops drugs for rare endocrine disorders. Prader-Willi syndrome, a terrible genetic disorder that causes young people to develop voracious appetites and which leads to severe obesity, is the focus of the company’s lead drug candidate. It’s entering a pivotal...
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12
Feb
2019

The Immune Sequencing Frontier (Take 2): Harlan and Chad Robins on The Long Run

Today’s guests on The Long Run are Harlan and Chad Robins. They are brothers and co-founders of Seattle-based Adaptive Biotechnologies. Chad is the CEO, and Harlan is the head of innovation. Harlan is also a faculty member at the Fred Hutchinson Cancer Research Center just down the street from Adaptive. Senior people in pharma R&D are quite familiar with Adaptive....
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30
Jan
2019

Finding a Way in Genomic Diagnostics: Bonnie Anderson of Veracyte on The Long Run

Bonnie Anderson is today’s guest on The Long Run. Bonnie is the CEO of Veracyte. It’s a genomic diagnostics company in South San Francisco. The company markets a line of tests for thyroid cancer, lung cancer, and idiopathic pulmonary fibrosis. Veracyte got started in 2008. Bonnie, as co-founder and CEO, was recruited by Kleiner Perkins Caufield & Byers and a...
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2
Jan
2019

From Merck Fast Track to Computer Chem Frontier: Karen Akinsanya on The Long Run

Today’s guest on The Long Run is Karen Akinsanya. Karen is the chief biomedical scientist at Schrodinger. The New York-based company is a leader in computational chemistry for drug discovery. The company is privately held, and not a household name. But some wealthy and powerful people know it well. Schrodinger counts Bill Gates and David E. Shaw, the hedge fund...
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26
Dec
2018

Messenger RNA Therapies That You May Not Have Heard Of: Ron Renaud on The Long Run

Today’s guest on The Long Run is Ron Renaud. Ron is the CEO of Lexington, Mass.-based Translate Bio. The company is working on messenger RNA therapies. You may have heard about this technology. mRNA molecules provide genetic instructions for making proteins. The idea is to restore functional proteins that, for one reason or another, have gone awry in a disease...
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14
Nov
2018

From Nova Scotia to the Forefront of Bio & Tech Investing: Julie Sunderland of Biomatics on The Long Run

Julie Sunderland is the guest on the latest episode of The Long Run podcast. She is a managing director at Biomatics Capital, a Seattle-based venture firm that invests in what it calls “data-enabled healthcare.” Before diving into that, as always, I want listeners to get to know the person making things happen, and how she got here. Sunderland her fellow...
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1
Nov
2018

Exploring Synthetic Lethal Cancer Drug Discovery: Barbara Weber on The Long Run

Today’s guest on The Long Run podcast is Barbara Weber. She is the CEO of Cambridge, Mass.-based Tango Therapeutics. Ever hear the saying ‘it takes two to tango?’ That’s where this startup draws its inspiration. It’s seeking to discover and develop synthetic lethal cancer drugs. These are intended to target two molecular vulnerabilities of a cancer cell, not just one,...
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17
Oct
2018

Making it Easy to Share Biological Data: John Wilbanks on The Long Run Podcast

John Wilbanks is today’s guest on The Long Run podcast. He’s the chief commons officer of Sage Bionetworks. He’s also a senior fellow with FasterCures. Sage, for those unfamiliar, is a nonprofit biomedical research organization, founded in Seattle in 2009 by a couple of veterans of Merck. Co-founders Stephen Friend and Eric Schadt recognized that no single company’s R&D labs,...
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25
Jul
2018

Finding the ‘Middle Market’ of Biotech VC: Chris Garabedian on The Long Run Podcast

Today’s guest on The Long Run podcast is Chris Garabedian. Garabedian is best known for his controversial stint as CEO of Cambridge, Mass.-based Sarepta Therapeutics, the developer of treatments for Duchenne Muscular Dystrophy. Whatever you may think of his tenure there — and the FDA’s decision to approve eteplirsen on a slim reed of clinical trial evidence – there is...
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