13
Jun
2023
Gilead Test Drives A-Alpha Bio Platform to Find Long-Acting Biologics Against HIV
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8
Jun
2023
Startup Profiles: Upstream Bio Gets Another $200M, Kate Therapeutics Debuts with $51M
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5
Jun
2023
Alkeus, a Bootstrap Success Story, Grows Up With $150M Series B
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1
Jun
2023
Pfizer’s RSV Vaccine OK’d, Coherus Challenges Humira, & Eikon Gets a Pipeline
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30
May
2023
From Structural Biology to Structuring Companies: Deb Palestrant on The Long Run
Today’s guest on The Long Run is Deb Palestrant. Deb is a partner with 5AM Ventures and the executive chair of the 4:59 Initiative. 5AM invests in early-stage startups working on a variety of novel biological targets and some of the emerging new treatment modalities – gene therapy, gene editing, oligonucleotides. As the name suggests, it’s not afraid to get... Read More
25
May
2023
ElevateBio Hauls in $401M, Blueprint Expands Label, & a String of Clinical Failures
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23
May
2023
Larkspur Gets $35.5M to Make Small Molecule Cancer Immunotherapies
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16
May
2023
Boundless Bio Gets $100M to Fight Cancer, NewLimit Gets $40M to Defy Aging
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11
May
2023
Thinking Big About Community Impact
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8
May
2023
Creating a New Class of Medicines: John Maraganore on The Long Run
Today’s guest on The Long Run is John Maraganore. John is best known as the former CEO of Alnylam Pharmaceuticals, the RNA interference drug developer. He spent 19 years there as CEO, before stepping down at the end of 2021. Alnylam figured out how to make a new therapeutic modality — gene-silencing with double-stranded oligonucleotide therapies. Alnylam’s technology has now... Read More
4
May
2023
Lilly’s Alzheimer’s Win, Astellas Breaks Out Checkbook, & a RSV Vaccine First
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27
Apr
2023
Big Week for RNA Medicines, BMS Gets a New Boss, and a Microbiome First
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26
Apr
2023
Orbital Secures $270M to Make New RNA Medicines
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25
Apr
2023
Vedanta Biosciences Secures $106.5M to Advance Oral Microbiome Therapies
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24
Apr
2023
Gene Editing Therapies Delivered In Vivo: Ensoma’s Emile Nuwaysir on The Long Run
Today’s guest on The Long Run is Emile Nuwaysir. Emile is the CEO of Boston-based Ensoma. Ensoma is developing gene-editing therapies that can be delivered in a single shot, in vivo, inside the body. The name is derived from the Greek word for ‘in the body.’ The basic idea is to make these gene editing medicines so they can be... Read More
20
Apr
2023
The Supreme Court and the FDA
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20
Apr
2023
Abdera Gets $142M To Make Potent, Safe, Radioantibodies for Cancer
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13
Apr
2023
The FDA’s Hour of Need, Digital Tx Pioneer Shuts Down, & HSBC Hires SVB Vets
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13
Apr
2023
Aer Therapeutics Gets $36M Series A to Break Down Mucus in Lungs
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12
Apr
2023
The Frontier of Epigenetic Editing: Chroma CEO Catherine Stehman-Breen
Today’s guest on The Long Run is Catherine Stehman-Breen. Catherine is the CEO of Boston-based Chroma Medicine. Chroma is working on therapies that control gene expression through epigenetic editing. People have heard a lot about editing of the genome with CRISPR, and then subsequent refinements of the technology known as base editing and prime editing. The question at Chroma is... Read More