By

Luke Timmerman

12
Apr
2023

The Frontier of Epigenetic Editing: Chroma CEO Catherine Stehman-Breen

Today’s guest on The Long Run is Catherine Stehman-Breen. Catherine is the CEO of Boston-based Chroma Medicine. Chroma is working on therapies that control gene expression through epigenetic editing. People have heard a lot about editing of the genome with CRISPR, and then subsequent refinements of the technology known as base editing and prime editing. The question at Chroma is...
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29
Mar
2023

Timmerman Traverse for Life Science Cares is Back

The next biotech team adventure is here. I’m thrilled to announce the Timmerman Traverse for Life Science Cares 2023. We’re on a mission to raise $1 million. We’re giving it all back to the most vulnerable people in the communities where we live and work. This trip involves shared sacrifice. We will cover 20+ miles and gain 8,000 feet of...
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14
Mar
2023

The Future of Neuroscience Drug R&D: Ryan Watts on The Long Run

Today’s guest on The Long Run is Ryan Watts. Ryan is the co-founder and CEO of South San Francisco-based Denali Therapeutics. Denali is one of the prominent development-stage biotech companies working on treatments for neurodegenerative diseases. It has a pipeline with seven drug candidates in clinical development. It’s developing small molecules and large molecules against a range of neurodegenerative diseases...
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28
Feb
2023

A Life in Biotech & the Cell Therapy Wave: David Hallal on The Long Run

Today’s guest on The Long Run is David Hallal. David is the CEO of Waltham, Mass.-based ElevateBio. ElevateBio describes itself as a technology-driven company for cell therapies. It has pulled together gene editing tools, induced pluripotent stem cells, and various viral vectors necessary to modify cells to fight cancer or treat other diseases. David co-founded ElevateBio in 2017 with Mitchell...
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14
Feb
2023

Engineered B-Cell Therapies for Cancer & Rare Diseases: Joanne Smith-Farrell on The Long Run

Today’s guest on The Long Run is Joanne Smith-Farrell. Joanne is the CEO of Cambridge, Mass.-based Be Biopharma. Many listeners of this show are familiar with the explosion of activity in cell therapy. Engineered T cell therapies have delivered extraordinary results for people with certain types of cancer. The success in these personalized T cell therapies, which get modified outside...
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1
Feb
2023

A Biotech Journalism Outlet Built to Last: Rick Berke on The Long Run

Today’s guest on The Long Run is Rick Berke. Rick is the co-founder and executive editor of STAT. Just about everyone who listens to The Long Run probably already reads STAT. If you don’t, you should. It’s become a go-to publication for breaking news, features, and in-depth investigative reporting across the world of biotech and healthcare. John Henry, the billionaire...
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19
Jan
2023

From Computational Discovery to a New Psoriasis Drug: Jeb Keiper on The Long Run

Today’s guest on The Long Run is Jeb Keiper. Jeb is the CEO of Boston-based Nimbus Therapeutics. Nimbus made news in December 2022 when it sold its experimental Tyk2 inhibitor to Takeda Pharmaceuticals for $4 billion upfront and $2 billion in potential milestones. The drug’s value skyrocketed when it hit the primary endpoint of a Phase 2b clinical trial for...
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