27
Jun
2022
Nucleate Doubles in Size, Enabling Young Scientists’ Entrepreneurial Dreams
Academia has a tradition of doing nothing, or next to nothing, to educate and encourage young people to learn about entrepreneurship. But whether academia wants it or not, it’s coming. Young scientists are taking matters into their own hands, organizing themselves in many major research hubs. Nucleate, the nonprofit providing free resources to empower a new generation of biotech entrepreneurs,... Read More
23
Jun
2022
Clinical Trials That Deliver Better Social and Financial Returns
Sometimes doing the right thing requires sacrifice. Other times, the right thing for human health can also be a shrewd business move. That was the intriguing result of a study on the returns sponsors can expect from decentralized trials. The study relied on data from Medable and the Tufts Center for the Study of Drug Development. Results were presented this... Read More
22
Jun
2022
Bringing Precision Medicine to Neuro: Ivana Magovcevic-Liebisch on The Long Run
Today’s guest on The Long Run is Ivana Magovcevic-Liebisch She is the CEO of Cambridge, Mass.-based Vigil Neuroscience. The story starts with Amgen. The big biotech made a strategic decision to get out of neuroscience in 2019. That meant a couple of drug programs targeting TREM2 came up for sale. One is a monoclonal antibody, and the other is a... Read More
16
Jun
2022
Day One Shines, Third Rock Carries On and Vertex/CRISPR Deliver
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15
Jun
2022
Third Rock Raises $1.1B Fund, Sticks With Its Knitting in a Downturn
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14
Jun
2022
Seattle Children’s Invests $45M in Minority Scientists Tackling Pediatric Disease
Many bright young people never get a chance to fulfill their potential as scientists because they never get on the usual scientific career on-ramps. Many young people who get sick struggle because no one had the motivation or the wherewithal to develop new treatments or diagnostics. Seattle Children’s Research Institute sees the problems, and has crafted a major initiative to... Read More
12
Jun
2022
Day One Shrinks Brain Tumors for Kids, Gears Up for First-Line Study
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9
Jun
2022
Daiichi’s Game-Changer, Resilience’s Big Week, and the FTC Scrutinizes PBMs
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7
Jun
2022
Rethinking Biotech Manufacturing: Rahul Singhvi on The Long Run
Today’s guest on The Long Run is Rahul Singhvi. Rahul is the co-founder and CEO of Resilience. The company made a splash in the fall of 2020, when it debuted with an $800 million Series A financing. Bob Nelsen of ARCH Venture Partners led the deal. The company has now raised a couple more rounds that add up to more... Read More
2
Jun
2022
Out in the Community in 2022
TR subscribers: I’m traveling more, and looking forward to seeing more of you in person. I’ll be at the BIO Convention in San Diego, June 13-15. They have plenty of outdoor patio space overlooking the ocean at the San Diego Convention Center. Let’s chat. While at BIO meeting people and gathering ideas, I’m also moderating a panel on improving diversity,... Read More
2
Jun
2022
Startup Profiles: Upstream Gets $200m for Asthma Antibody; Transition Fetches $50m for Condensate Drug Discovery
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26
May
2022
Managing Through a Hard Time Like No Other
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23
May
2022
Building a New Type of Drug Discovery Engine: Chris Gibson on The Long Run
Today’s guest on The Long Run is Chris Gibson. Chris the co-founder and CEO of Salt Lake City-based Recursion. The company was founded in 2013 when Chris was working in the lab of Dean Li at the University of Utah. The idea at Recursion is to do what it calls “industrialized drug discovery.” It combines some of the common tools... Read More
19
May
2022
A Path Forward for More Biotech Workers
Biotech needs more workers. More people who don’t have PhDs and MDs. The industry is 40 years old, and maturing. More companies are developing commercial products. Someone needs to make these products with precision, and at scale. Given the sophisticated nature of the products (cell therapy, gene therapy, advanced biologics, RNA medicines), the fragile global supply chains, and the importance... Read More
17
May
2022
Remix Gets $70m for Small Molecules to Alter RNA Processing
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10
May
2022
MOMA Gets $150M to Make Small Molecules Against ATPases, Laborers of the Cell
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9
May
2022
Fighting Cancer With Food and Drugs: Lew Cantley and Sid Mukherjee on The Long Run
Today’s guests on The Long Run are Lewis Cantley and Siddhartha Mukherjee. They are co-founders of San Francisco-based Faeth Therapeutics. Cantley, who recently moved to Dana Farber Cancer Institute, is a scientist well-known for his work on cancer metabolism. He discovered the PI3kinase pathway that’s an important regulator of normal cell growth, proliferation, metabolism – and which can become activated... Read More
5
May
2022
An Old Idea Whose Time Has Come
People are returning to the office. Many are rethinking the basics of work. So many people are exhausted and anxious. Biotech leaders are thinking carefully about how to proceed. An R&D-based industry needs people in environments that allow them to be energized, creative, collaborative. Here’s one simple idea: Walking meetings. The “walk and talk” business meeting isn’t new. But we... Read More
3
May
2022
Dianthus Gets $100m to Take Complement Inhibition to a New Level
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28
Apr
2022
A Big Opportunity in Obesity
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