23
Mar
2025
How a Dark Horse Candidate is Upending the Sequencing Market
Before Roche officially announced their new sequencer in a pre-AGBT webinar in February 2025, only true sequencing aficionados had heard of Stratos Genomics or Sequencing by Expansion (SBX). The SBX chemistry underlying Roche’s new sequencer was developed by Stratos Genomics, which Roche acquired in 2020 and paired with nanopore sensors from Genia Technologies, which Roche acquired way back in 2014.... Read More
20
Mar
2025
Curevo and Arbor Defy Gravity, Cargo Hits the Wall, & AZ Bets on In Vivo
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18
Mar
2025
See the Photos from TR10 West
Thanks to everyone who attended the TR10 anniversary party Mar. 13 at Adaptive Biotechnologies. The toasts and roasts were funny, perceptive and heartfelt. It was a joyous occasion. Enjoy a few photos. Click to enlarge. Photos by Robert Wade.
18
Mar
2025
See the Photos from TR10 East
Thanks to everyone who attended the TR10 anniversary party Mar. 6 at Alnylam Pharmaceuticals. The toasts and roasts were funny, perceptive and heartfelt. There was a joyful community spirit in the room. Enjoy a few photos. Click to enlarge. Photos by Mike Mejia.
18
Mar
2025
Arbor Survives Winter, Gets $73.9M to Take Gene Editing to the Clinic
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17
Mar
2025
Why Cell & Gene Therapy Companies Should Talk with RFK Jr.
As the CEO of the cell and gene therapy advocacy organization the Alliance for Regenerative Medicine (ARM), I’ve been asked one question more than any other amid the constant barrage of news headlines the past two months. How are you approaching the Trump Administration? I hear it from across our community, including biotechnology companies, academic and medical research institutions, patient... Read More
17
Mar
2025
CAR-T cell Therapies Made In the Body: Andy Scharenberg on The Long Run
Andy Scharenberg is today’s guest on The Long Run. Andy is the co-founder and CEO of Seattle-based Umoja Biopharma. The company is developing in vivo CAR-T cell therapies. The idea is to use gene therapy, delivered in a single shot, that can reprogram T cells of the immune system to recognize markers on cancer cells and then hunt down cancer... Read More
17
Mar
2025
Curevo Captures $110M to Develop a More Tolerable Shingles Vaccine
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13
Mar
2025
Protagonist Delivers, BMS Bargain Hunts, and Zealand Goes Major League
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11
Mar
2025
NIH Cuts Hit Young Scientists the Hardest
[Editor’s note: David Baker gave this speech to Seattle community leaders Mar. 10, at a celebration of his 2024 Nobel Prize in Chemistry.] Let me just briefly tell you how innovation arises in biomedicine and where drug discoveries come from. A large percentage of the innovation is made at universities by graduate students and postdocs. Often, they take their ideas... Read More
9
Mar
2025
Scientists Standing Up in Seattle
Several thousand scientists gathered Friday in Seattle for one of the nationwide “Stand Up for Science” protests. People studying a range of disciplines — biology, climate change, public health and more — took a break from the lab to protest cuts to federal spending on science and mass firings. Morale had been low for weeks among many attendees, but Friday... Read More
6
Mar
2025
Biotech Legend Retires, Jazz Buys Glioma Drug, & FDA Shakeup
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5
Mar
2025
Sluggish Corporate AI Adoption Has Motivated Entrepreneurs To Pick Their Spots
As economic historian Carlota Perez has described, there is typically a significant time lag between when the promise of novel technology begins to emerge and the productive deployment of this technology at scale; TR readers will recall the discussion here from June 2023. Today, we are seeing this with generative AI, an emerging technology that everyone is still trying to... Read More
4
Mar
2025
Flashback: Q&A on Founding TR
[Dear Readers: This Q&A from the Knight Science Journalism at MIT blog on Feb. 3, 2015 captures my thoughts on founding TR and where biotech was going. Thank you for your support. — Luke ] By Wade Roush For writers, part of the fuss about the Web explosion of the late 1990s was that it was finally possible to cut... Read More
3
Mar
2025
A Woman in the TechBio Arena: Najat Khan on The Long Run
Najat Khan is today’s guest on The Long Run. She is the chief R&D and chief commercial officer of Salt Lake City-based Recursion. The company is one of the first-generation companies that have sought to reinvent drug R&D from the ground up with automated technologies that collect a lot of biological data and then analyze that data with AI algorithms.... Read More
27
Feb
2025
Bluebird Fire Sale, Regeneron’s Gene Therapy for Deafness, & Eikon Raises a Bundle
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27
Feb
2025
How Maze Therapeutics Navigated Genetics-Based Drug Discovery
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26
Feb
2025
How to Know when a Company Should Throw in the Towel
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24
Feb
2025
Rewiring, Not Retiring: Health and Innovation for the Vanguard Generation
Most of my columns tend to focus on the importance and difficulty of applying emerging technologies to biopharma R&D, aiming to accelerate the delivery of impactful medicines to patients. Yet, as long-time readers know, I have an enduring interest in how to sustain health and ward off illness, a discipline that’s sometimes called Preventive Medicine, Preemptive Health, or, the term... Read More
24
Feb
2025
Defend Young Scientists
Biotech thrives on the creative dynamism of young scientists. Always has. Young scientists are under pressure. NIH grants are on hold. If the NIH budget is gutted, and a generation is forced to find other ways to earn a living, then the biotech industry will lose. It might not be clear for the next couple of quarters or next couple... Read More