11
May
2023
Thinking Big About Community Impact
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8
May
2023
Creating a New Class of Medicines: John Maraganore on The Long Run
Today’s guest on The Long Run is John Maraganore. John is best known as the former CEO of Alnylam Pharmaceuticals, the RNA interference drug developer. He spent 19 years there as CEO, before stepping down at the end of 2021. Alnylam figured out how to make a new therapeutic modality — gene-silencing with double-stranded oligonucleotide therapies. Alnylam’s technology has now... Read More
4
May
2023
Lilly’s Alzheimer’s Win, Astellas Breaks Out Checkbook, & a RSV Vaccine First
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27
Apr
2023
Big Week for RNA Medicines, BMS Gets a New Boss, and a Microbiome First
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26
Apr
2023
Orbital Secures $270M to Make New RNA Medicines
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25
Apr
2023
Vedanta Biosciences Secures $106.5M to Advance Oral Microbiome Therapies
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24
Apr
2023
Gene Editing Therapies Delivered In Vivo: Ensoma’s Emile Nuwaysir on The Long Run
Today’s guest on The Long Run is Emile Nuwaysir. Emile is the CEO of Boston-based Ensoma. Ensoma is developing gene-editing therapies that can be delivered in a single shot, in vivo, inside the body. The name is derived from the Greek word for ‘in the body.’ The basic idea is to make these gene editing medicines so they can be... Read More
20
Apr
2023
The Supreme Court and the FDA
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20
Apr
2023
Abdera Gets $142M To Make Potent, Safe, Radioantibodies for Cancer
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13
Apr
2023
The FDA’s Hour of Need, Digital Tx Pioneer Shuts Down, & HSBC Hires SVB Vets
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13
Apr
2023
Aer Therapeutics Gets $36M Series A to Break Down Mucus in Lungs
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12
Apr
2023
The Frontier of Epigenetic Editing: Chroma CEO Catherine Stehman-Breen
Today’s guest on The Long Run is Catherine Stehman-Breen. Catherine is the CEO of Boston-based Chroma Medicine. Chroma is working on therapies that control gene expression through epigenetic editing. People have heard a lot about editing of the genome with CRISPR, and then subsequent refinements of the technology known as base editing and prime editing. The question at Chroma is... Read More
12
Apr
2023
Function Gets $28M to Make Personalized Cancer Genomics to the Next Level
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6
Apr
2023
CRISPR, Vertex Seek FDA Milestone, Canaan Pulls in $850M, & Cutting Out the Middleman
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29
Mar
2023
Timmerman Traverse for Life Science Cares is Back
The next biotech team adventure is here. I’m thrilled to announce the Timmerman Traverse for Life Science Cares 2023. We’re on a mission to raise $1 million. We’re giving it all back to the most vulnerable people in the communities where we live and work. This trip involves shared sacrifice. We will cover 20+ miles and gain 8,000 feet of... Read More
28
Mar
2023
Treating a Common, Underappreciated Disease: Eric Dobmeier on The Long Run
Today’s guest on The Long Run is Eric Dobmeier. Eric is the CEO of Seattle-based Chinook Therapeutics. Chinook is seeking to develop drugs for kidney diseases. About 10 percent of people on Earth are estimated to have some degree of chronic kidney disease. It ranges from mild forms all the way through end-stage renal disease that requires dialysis. America spends... Read More
22
Mar
2023
Flare Therapeutics Gets $123M to Make Drugs Against Elusive Transcription Factors
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18
Mar
2023
Takeda Oral Tyk2 Inhibitor, Acquired in Nimbus Deal, Raises the Bar on Psoriasis
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16
Mar
2023
Pfizer Acquires Seagen, Sanofi & Novo Cut Insulin Prices, & Illumina’s Proxy Fight
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15
Mar
2023
Big Pharma, VCs Bet $105M on Mediar’s Antibodies for Fibrotic Diseases
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