19
Jan
2023
From Computational Discovery to a New Psoriasis Drug: Jeb Keiper on The Long Run
Today’s guest on The Long Run is Jeb Keiper. Jeb is the CEO of Boston-based Nimbus Therapeutics. Nimbus made news in December 2022 when it sold its experimental Tyk2 inhibitor to Takeda Pharmaceuticals for $4 billion upfront and $2 billion in potential milestones. The drug’s value skyrocketed when it hit the primary endpoint of a Phase 2b clinical trial for... Read More
19
Jan
2023
Concert Gets Acquired, Structure Tees Up IPO, & a Proposed Noncompete Ban
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12
Jan
2023
JPM Vibes, Verily Cuts Back, & Eisai’s Transparent Price
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5
Jan
2023
J&J Walks Away from Fate, Century Cuts Back, & Moderna’s Strategic Buy
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4
Jan
2023
Belharra Gets $130M from Versant, Genentech For Chemoproteomic Discovery
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3
Jan
2023
From Musician to Tech to Biotech Investor: D.A. Wallach on The Long Run
Today’s guest on The Long Run is D.A. Wallach. D.A. is the founder and general partner of Time BioVentures. Time BioVentures is a relative newcomer to the biotech world, investing out of a $100 million inaugural fund. The strategy is to invest in companies seeking to make a big impact in therapeutics, diagnostics, research tools, and healthcare delivery models. D.A.... Read More
21
Dec
2022
Madrigal’s NASH Persistence Pays, Gilead’s Mixed TIGIT Bag, & Zymeworks’ Rebound
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19
Dec
2022
A New Way to Treat Depression: Barry Greene on The Long Run
Today’s guest on The Long Run is Barry Greene. Barry is the CEO of Cambridge, Mass.-based Sage Therapeutics. Sage is developing a new medicine for the treatment of major depressive disorder and postpartum depression. Sage, and its partner, Biogen, recently completed a New Drug Application to the FDA for permission to start marketing zuranolone. The drug is a once-daily oral... Read More
15
Dec
2022
Amgen Buys Horizon, Mirati’s KRAS Drug OK, & Nimbus’s Tyk2 Windfall
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10
Dec
2022
Sutro Delivers Complete Responses Against Deadly Pediatric Acute Myeloid Leukemia
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8
Dec
2022
Summit’s Bold Bid, Karuna’s Commercial Boss, & Gossamer’s Stumble
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1
Dec
2022
Alzheimer’s Debate, Nimbus to Challenge BMS, & a Microbiome First
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29
Nov
2022
Cajal Comes Out of Stealth with $96M for Alzheimer’s, Parkinson’s Drug Discovery
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7
Nov
2022
Delivery of Genetic Medicines: Shehnaaz Suliman on The Long Run
Today’s guest on The Long Run is Shehnaaz Suliman. Shehnaaz is the CEO of Menlo Park, California-based ReCode Therapeutics. Recode is working on lipid nanoparticles to improve the delivery of genetic medicines. These little packages have made it possible to deliver billions of mRNA COVID vaccines in people’s arms, saving millions of lives. It’s been two decades of hard work.... Read More
27
Oct
2022
Vaxcyte Takes on Pfizer, Novartis Challenges AZ, & Time Gets $100M
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26
Oct
2022
Single-Cell Analysis for Precision Medicine: Tariq Kassum on The Long Run
Today’s guest on The Long Run is Tariq Kassum. Tariq is the CEO of Cambridge, Mass.-based Celsius Therapeutics. Celsius emerged on the scene in May 2018 with a $65 million Series A led by Third Rock Ventures. It was built on the conviction that single cell analysis will shed light on new targets for the treatment of cancer, autoimmunity and... Read More
26
Oct
2022
Variant Bio Strikes New Pharma Bargain, Shares Benefits of Human Genetic Research
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20
Oct
2022
Bezos Bets on Fred Hutch, Prime Medicine Bucks the Trend, and PacBio Throws Down
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14
Oct
2022
Matchpoint Gets $100M to Take Covalent Binders Into Autoimmune Disease
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11
Oct
2022
Protein Degraders For Outside the Cell: Aetna Wun Trombley on The Long Run
Today’s guest on The Long Run is Aetna Wun Trombley. Aetna is the CEO of South San Francisco-based Lycia Therapeutics. Many in biotech know about targeted protein degraders. Arvinas and Kymera Therapeutics are a couple of the well-known companies that make these drugs which work to inhibit intracellular proteins. This approach has drawn a lot of excitement because it can... Read More