19
Dec
2024
Vertex Pain Drug Fails, Puretech Delivers for IPF, Merck Dumps TIGIT, LAG3 Antibodies
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12
Dec
2024
The Past, Present and Future of RNAi Therapies: Kevin Fitzgerald on The Long Run
Today’s guest on The Long Run is Kevin Fitzgerald. Kevin is the chief scientific officer of Cambridge, Mass.-based Alnylam Pharmaceuticals. He joined the company way back in 2005, when it was aspiring to create a new class of RNA interference medicines. These are sometimes referred to as “gene silencing” drugs. They are designed to shut down the production of disease-related... Read More
12
Dec
2024
ASH Recap, Dimension Captures $500M, & AbbVie’s New Parkinson’s Drug
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9
Dec
2024
Dimension Raises $500M to Seize the Tech-Driven Biology Future
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9
Dec
2024
ASH Highlights: Beam Base Editing, Novo’s Oral Pill Advance for Sickle Cell
Please subscribe and tell your friends why it’s worthwhile. Quality journalism costs money. When you subscribe to Timmerman Report at $199 per year, you reward quality independent biotech reporting, and encourage more. Subscribe Now Sign in to your account.
5
Dec
2024
Lilly Beats Novo, Amgen’s So-So Obesity Data & Atlas Stays Lean & Mean
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5
Dec
2024
Computational Techniques Are Driving a Tidal Shift in Therapeutic Protein Design
I recently attended the Molecular Machine Learning (MoML) Conference sponsored by the MIT Jameel Clinic, an institute focused on cutting-edge machine learning (ML) techniques in the life sciences. Computational approaches to drug discovery and development were the centerpiece of the symposium. Investor sentiment for ML-centric discovery biotechs has been turbulent recently, but researchers at MoML were widely and consistently enthusiastic.... Read More
4
Dec
2024
Versant, Novo-backed Antag Gets $84M for Weight Loss Drug with Combo Potential
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27
Nov
2024
What Should We Pay for a Good Death?
The intensive care unit in a hospital is a place where hope and despair whisper back and forth in the air. For Richard, the emotional seesaw was becoming all too familiar. This was his third ICU stay in a month, and the ninth brush with life and death from pulmonary arterial hypertension. No matter how hard the day was, he... Read More
26
Nov
2024
Meet the 2025 Timmerman Traverse for Damon Runyon Cancer Research Team
I’m excited to announce the 2025 Timmerman Traverse for Damon Runyon Cancer Research Foundation team. This group of 17 men and women are on a mission to raise more than $700,000 for the next generation of outstanding cancer researchers. In April, we’ll come together on the world-famous trek to Everest Base Camp, elevation 17,600 feet. We’re raising awareness for cancer... Read More
25
Nov
2024
How to Quit Smoking and Prevent Cancer: Jonathan Bricker on The Long Run
Today’s guest on The Long Run is Jonathan Bricker. Jonathan is a professor in the cancer prevention program that’s part of the Public Health Sciences Division at Fred Hutchinson Cancer Center in Seattle. This episode is a little different than most. Jonathan is a clinical psychologist by training. His research team focuses on how to use a combination of technology... Read More
24
Nov
2024
A Story of Hope For Kids With Rare Disease
As we head into Thanksgiving, I wanted to share a story that highlights the promise and possibility that can emerge from a devastating diagnosis, and emphasizes what can happen when industry, academia, and — especially — impassioned parents and advocates join forces. Consider the devasting rare genetic disease, spinal muscular atrophy, or SMA. According to Cure SMA, SMA is “a... Read More
21
Nov
2024
Dr. Oz to CMS, Amgen and Pfizer Get New CSOs, & SubQ Keytruda Arrives
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21
Nov
2024
Speaking Up for Science and Health. Even When Inconvenient
“By their fruits, ye shall know them” –Matthew 7:16 Immediately following the election of Donald Trump, a number of publications asked leaders of the biopharmaceutical industry and investment community to share their thoughts on how his likely policies and appointees to key positions of leadership will affect our industry. Many of these leaders counseled us to “wait and see” before making... Read More
21
Nov
2024
Startup Snapshots: A Tetra-Binder for Obesity, and a ‘Mirror Peptide’ Engine
Please subscribe and tell your friends why it’s worthwhile. Quality journalism costs money. When you subscribe to Timmerman Report at $199 per year, you reward quality independent biotech reporting, and encourage more. Subscribe Now Sign in to your account.
20
Nov
2024
US-China Partnership: Just Hitting its Stride, and Now Threatened
Curon, Chimagen, Hengrui, LaNova…the list goes on of Chinese biotech companies that have recently licensed potential blockbuster drug candidates for cancer, autoimmunity and more to US pharma and biotech companies for further development. Over the past year or so, there has been a dramatic increase in both the number of deals to obtain rights to assets discovered in China, and... Read More
19
Nov
2024
A Tale of Two Neds: Jupiter Debuts with $70M To Invest in Startups
Please subscribe and tell your friends why it’s worthwhile. Quality journalism costs money. When you subscribe to Timmerman Report at $199 per year, you reward quality independent biotech reporting, and encourage more. Subscribe Now Sign in to your account.
18
Nov
2024
Coastal Culture Clash Around AI in Biotech
“Does the crowd understand? Is it East versus West Or man against man? Can any nation stand alone?” Burning Heart, by Survivor – Rocky IV In national politics, the culture wars may pit the coasts against the rest of the country. In biotech, however, the AI culture war seems to pit the coasts against each other. Consider this recent LinkedIn... Read More
18
Nov
2024
In Vivo Gene Therapy Isn’t The Answer. Sickle Cell Patients Need Today’s Treatments
On his fourth birthday, Adamu couldn’t celebrate. The boy, from a rural village in Nigeria, had a flare up of his sickle cell disease known as a pain crisis. His parents tell me the rare days when he’s full of energy and playing with his friends feel like a precious gift. This year, he was given a cruel reminder of... Read More
14
Nov
2024
RFK Jr. to HHS. I Was Wrong
Please subscribe and tell your friends why it’s worthwhile. Quality journalism costs money. When you subscribe to Timmerman Report at $199 per year, you reward quality independent biotech reporting, and encourage more. Subscribe Now Sign in to your account.