11
Oct
2017

George Yancopoulos on Threading the Price Needle, and Building a Biotech to Last

George Yancopoulos, the president and chief scientific officer, started his biotech career in 1989 at Regeneron Pharmaceuticals. He’s been there ever since, and has pretty much seen it all.

It was a pleasure to have him as the guest for Episode 3 of The Long Run podcast.

Yancopoulos, in this recording at Regeneron offices in Tarrytown, NY, talks about how he and CEO Len Schleifer built the company together.

George Yancopoulos, president and chief scientist, Regeneron Pharmaceuticals

These two recall the lean years when investors wondered if they were running a science project, or building a real drug company. But Regeneron has broken out as one of biotech’s big successes. The company has developed 6 FDA-approved drugs so far. It’s the third-best performing stock in the S&P 500 over the past decade. Now Regeneron is attempting to the lay the foundation for many more drugs by investing in an ambitious genomics-based discovery center.

Yancopoulos is a forceful personality. You’ll hear his passion for science come through clearly in this conversation.

Before you take a listen, a couple quick plugs. If you like this show, you’ll love my subscription newsletter, Timmerman Report. You can go to timmermanreport.com to subscribe, either as an individual, or with a group discount for your company or university.

If you are interested in sponsorship opportunities for this podcast, this will be a great way to get your company’s name in front of a high-value audience of biotech executives and investors. Send me an email. luke@timmermanreport.com.

The next episode of The Long Run will feature a conversation with Richard Pops, the CEO of Alkermes, about his company’s anti-addiction drug, and the role it can play in combating the opioid painkiller epidemic.

This was a serious conversation, and an uncomfortable one at times. Some in industry have been irresponsible in overmarketing opioid painkillers. There is no silver bullet for this scourge. This will take a long-term push from multiple players – doctors, public health authorities, law enforcement, and the pharmaceutical industry. You won’t want to miss that upcoming conversation with Richard Pops.

Now, join me for The Long Run. Thanks for listening.

13
Sep
2017

The Long Run, Ep. 1: Conversation with Alnylam CEO John Maraganore

Podcast listeners, check it out: Today, I’m starting a new podcast for biotech adventurers like you – executives, investors, scientists.

It’s called The Long Run. Here’s the gist:

Antarctic explorer Ernest Shackleton, if he were alive, would appreciate biotech. Today’s scientific entrepreneurs must be ready for the “hazardous journey, bitter cold, long months of complete darkness, constant danger, safe return doubtful, honor and recognition in case of success.” Today, the men and women who strive to apply science for the betterment of human health have a historic opportunity. They need stamina, and resilience, to achieve something meaningful. Biotech’s relationship with the society that sustains it has never been more tenuous.

This show will provide a forum for thoughtful conversations with biotech leaders, typically between 45-60 minutes, airing every other week.

John Maraganore, CEO, Alnylam Pharmaceuticals.

The debut episode (click here) features John Maraganore, the CEO of Alnylam Pharmaceuticals and the chairman of the Biotechnology Innovation Organization. We covered some of Alnylam’s 15-year history, making the transition to a commercial enterprise on the cusp of long-awaited Phase III clinical trial data, and the industry’s ongoing problem with drug pricing.

LISTEN

Like all podcasts, this show is being made free to all listeners – no TR subscription necessary. As an independent production of Timmerman Report, it will be available here first.

The next episode of The Long Run will feature Katrine Bosley, CEO of Editas Medicine, a drugmaker based on CRISPR-based genome editing technology. In Ep. 3, hear Regeneron Pharmaceuticals chief scientist George Yancopoulos talk passionately about creating a scientific culture that is so productive at creating new medicines that it doesn’t need to resort to price-gouging stunts. Expect a wide range of fascinating people and topics to come over time.

Thanks go out to my excellent collaborators. Pedro Rosado of Headstepper Media was the editor and producer. Music comes from D.A. Wallach. Todd Bennings created the logo. Steve White developed the landing page on TimmermanReport.com.

If you, or someone you know, is interested in sponsoring The Long Run, let’s talk. This will represent a rare opportunity for one, maybe two, sponsors to deeply engage with biotech leaders who will be listening. Email: luke@timmermanreport.com

Don’t miss an episode. Subscribe for free at the links below. Thanks for listening!