18
May
2023
Anthony Mancini of Genmab on Growing Your Company Together with Partners
Anthony Mancini is the chief operating officer of Denmark-based Genmab, one of the leading innovators of antibody therapies for patients living with cancer and other serious diseases. After many years working as a behind-the-scenes innovator, Genmab is now becoming a significant commercial entity. In 2021, the company began marketing its first commercial product, Tidvak® (tisotumab vedotin) for the treatment of... Read More
16
May
2023
Boundless Bio Gets $100M to Fight Cancer, NewLimit Gets $40M to Defy Aging
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15
May
2023
Biopharma Innovation – Beyond The Breathless Headlines
Biopharma relies on innovation to stay in business. Success depends on our collective ability to discover, develop, and deliver new products that cure or meaningfully mitigate disease over and over again. Patents allow for innovators to be rewarded, for a while. When patents expire, allowing us to purchase powerful generic medications like atorvastatin for pennies, manufacturers must come up with... Read More
11
May
2023
Thinking Big About Community Impact
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8
May
2023
Creating a New Class of Medicines: John Maraganore on The Long Run
Today’s guest on The Long Run is John Maraganore. John is best known as the former CEO of Alnylam Pharmaceuticals, the RNA interference drug developer. He spent 19 years there as CEO, before stepping down at the end of 2021. Alnylam figured out how to make a new therapeutic modality — gene-silencing with double-stranded oligonucleotide therapies. Alnylam’s technology has now... Read More
4
May
2023
Lilly’s Alzheimer’s Win, Astellas Breaks Out Checkbook, & a RSV Vaccine First
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1
May
2023
Preserving the Biotech Social Contract – We Should All Be Pitching In
[Editor’s Note: This is a preface by Jeremy Levin supporting the following essay by Steve Potts.] Biotech is an industrial tapestry woven together by remarkable people with deep intellect, determination, passion, and bravery all driven to create the next and best medicine. Underpinning it is an immense and complex infrastructure including capital formation, regulatory processes, patient advocacy, policy making, health... Read More
27
Apr
2023
Big Week for RNA Medicines, BMS Gets a New Boss, and a Microbiome First
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26
Apr
2023
Orbital Secures $270M to Make New RNA Medicines
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25
Apr
2023
Vedanta Biosciences Secures $106.5M to Advance Oral Microbiome Therapies
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24
Apr
2023
Gene Editing Therapies Delivered In Vivo: Ensoma’s Emile Nuwaysir on The Long Run
Today’s guest on The Long Run is Emile Nuwaysir. Emile is the CEO of Boston-based Ensoma. Ensoma is developing gene-editing therapies that can be delivered in a single shot, in vivo, inside the body. The name is derived from the Greek word for ‘in the body.’ The basic idea is to make these gene editing medicines so they can be... Read More
20
Apr
2023
The Supreme Court and the FDA
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20
Apr
2023
Abdera Gets $142M To Make Potent, Safe, Radioantibodies for Cancer
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19
Apr
2023
The “D” Word: Delivery is the Next Frontier for Genetic Medicines
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13
Apr
2023
The FDA’s Hour of Need, Digital Tx Pioneer Shuts Down, & HSBC Hires SVB Vets
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13
Apr
2023
Aer Therapeutics Gets $36M Series A to Break Down Mucus in Lungs
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12
Apr
2023
The Frontier of Epigenetic Editing: Chroma CEO Catherine Stehman-Breen
Today’s guest on The Long Run is Catherine Stehman-Breen. Catherine is the CEO of Boston-based Chroma Medicine. Chroma is working on therapies that control gene expression through epigenetic editing. People have heard a lot about editing of the genome with CRISPR, and then subsequent refinements of the technology known as base editing and prime editing. The question at Chroma is... Read More
12
Apr
2023
Function Gets $28M to Make Personalized Cancer Genomics to the Next Level
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10
Apr
2023
In Support of FDA’s Authority to Regulate Medicines
On Friday, April 7, a federal judge with no scientific training fundamentally undermined the bipartisan authority granted by Congress to the Food and Drug Administration to approve and regulate safe, effective medicines for every American. District Judge Matthew Kacsmaryk issued a decision that overturns the FDA’s 23-year-old approval of mifepristone, the primary medicine used in abortion and miscarriage care, and... Read More
8
Apr
2023
Tech, Pharma, and the Uneven Distribution of the AI-Enabled Future
The worlds of technology and entrepreneurship are captivated by recent advances in generative AI and large language models (LLMs). The arrival of ChatGPT, developed by OpenAI (a startup partnered with Microsoft), caused Google to declare a “Code Red,” akin to “pulling the fire alarm,” the New York Times explained. The latest class of startups at Y Combinator are reportedly flocking... Read More