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17
Jun
2023

Learning From History How to Think About the Technology of the Moment

Generative AI, the transformative technology of the moment, exploded onto the scene with the arrival in late 2022 of chatGPT, an AI-powered chatbot developed by the company OpenAI.  After only five days, a million users had tried the app; after two months: 100 million, the fastest growth ever seen for a consumer application. TikTok, the previous record holder, took nine...
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4
Jun
2023

Pharma R&D Execs Offer Extravagant Expectations for AI But Few Proof Points

As the excitement around generative AI sweeps across the globe, biopharma R&D groups (like most everyone else) are actively trying to figure out how to leverage this powerful but nascent technology effectively, and in a responsible fashion. In separate conversations, two prominent pharma R&D executives recently sat down with savvy healthtech VCs to discuss how generative AI specifically, and emerging...
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30
May
2023

From Structural Biology to Structuring Companies: Deb Palestrant on The Long Run

Today’s guest on The Long Run is Deb Palestrant. Deb is a partner with 5AM Ventures and the executive chair of the 4:59 Initiative. 5AM invests in early-stage startups working on a variety of novel biological targets and some of the emerging new treatment modalities – gene therapy, gene editing, oligonucleotides. As the name suggests, it’s not afraid to get...
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21
May
2023

Big, If True: Opportunities and Obstacles Facing AI (Plus: Summer Reading)

Today, we’ll begin with a consideration of the promise for AI some experts see in healthcare and biopharma. Next, we’ll look at some of the obstacles – some technical, some organizational – and re-visit the eternal “data parasite” debate. Finally, we’ll conclude with a few suggestions for summer reading. The AI Opportunity: Elevating Healthcare for All Earlier this month, I...
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18
May
2023

Anthony Mancini of Genmab on Growing Your Company Together with Partners

Anthony Mancini is the chief operating officer of Denmark-based Genmab, one of the leading innovators of antibody therapies for patients living with cancer and other serious diseases. After many years working as a behind-the-scenes innovator, Genmab is now becoming a significant commercial entity. In 2021, the company began marketing its first commercial product, Tidvak® (tisotumab vedotin) for the treatment of...
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15
May
2023

Biopharma Innovation – Beyond The Breathless Headlines

Biopharma relies on innovation to stay in business. Success depends on our collective ability to discover, develop, and deliver new products that cure or meaningfully mitigate disease over and over again. Patents allow for innovators to be rewarded, for a while. When patents expire, allowing us to purchase powerful generic medications like atorvastatin for pennies, manufacturers must come up with...
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11
May
2023

Thinking Big About Community Impact

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8
May
2023

Creating a New Class of Medicines: John Maraganore on The Long Run

Today’s guest on The Long Run is John Maraganore. John is best known as the former CEO of Alnylam Pharmaceuticals, the RNA interference drug developer. He spent 19 years there as CEO, before stepping down at the end of 2021. Alnylam figured out how to make a new therapeutic modality — gene-silencing with double-stranded oligonucleotide therapies. Alnylam’s technology has now...
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