12
Jan
2023
JPM Vibes, Verily Cuts Back, & Eisai’s Transparent Price
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5
Jan
2023
J&J Walks Away from Fate, Century Cuts Back, & Moderna’s Strategic Buy
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5
Jan
2023
Oui Therapeutics: Shifting the Clinical, Societal and Business Impact of Suicide
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4
Jan
2023
Belharra Gets $130M from Versant, Genentech For Chemoproteomic Discovery
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3
Jan
2023
From Musician to Tech to Biotech Investor: D.A. Wallach on The Long Run
Today’s guest on The Long Run is D.A. Wallach. D.A. is the founder and general partner of Time BioVentures. Time BioVentures is a relative newcomer to the biotech world, investing out of a $100 million inaugural fund. The strategy is to invest in companies seeking to make a big impact in therapeutics, diagnostics, research tools, and healthcare delivery models. D.A.... Read More
21
Dec
2022
Madrigal’s NASH Persistence Pays, Gilead’s Mixed TIGIT Bag, & Zymeworks’ Rebound
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19
Dec
2022
A New Way to Treat Depression: Barry Greene on The Long Run
Today’s guest on The Long Run is Barry Greene. Barry is the CEO of Cambridge, Mass.-based Sage Therapeutics. Sage is developing a new medicine for the treatment of major depressive disorder and postpartum depression. Sage, and its partner, Biogen, recently completed a New Drug Application to the FDA for permission to start marketing zuranolone. The drug is a once-daily oral... Read More
15
Dec
2022
Amgen Buys Horizon, Mirati’s KRAS Drug OK, & Nimbus’s Tyk2 Windfall
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15
Dec
2022
Prescribing Cancer Drugs Off-Label is Tricky. Transparency and Standards Are Needed
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14
Dec
2022
Reprofiling ‘Drug Repurposing’
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10
Dec
2022
Sutro Delivers Complete Responses Against Deadly Pediatric Acute Myeloid Leukemia
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8
Dec
2022
Summit’s Bold Bid, Karuna’s Commercial Boss, & Gossamer’s Stumble
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4
Dec
2022
Hot Topics in Biopharma: Initial Impact of Digital, Data Dilemmas in Clinical Studies, and the Search for ‘New Normal’
For today: topics relevant to many drug developers (and others): The initial impact of digital The dilemma of data collection in early clinical studies The elusive search for “new normal” ways of working Initial impact of digital in biopharma The sexy promise of digital/data/AI in biopharma was that emerging digital technologies were going to solve our most important and vexing... Read More
1
Dec
2022
Alzheimer’s Debate, Nimbus to Challenge BMS, & a Microbiome First
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29
Nov
2022
Cajal Comes Out of Stealth with $96M for Alzheimer’s, Parkinson’s Drug Discovery
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22
Nov
2022
Two Hard Lessons Learned from the Genocea Biosciences Experience
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15
Nov
2022
Team Julie: Fighting Back Against Glioblastoma
Thirty-seven years ago, I met a lovely and talented young woman while we were both pursuing our PhDs. We were married during our last year in graduate school, and have spent every day since raising a family; working in STEM-Medicine careers; and engaging with our communities. We had just retired in 2019 and begun making plans to travel and enjoy... Read More
14
Nov
2022
ICYMI – Recommended Reading and Listening for Biotech Innovators
Searching for a good listen or an interesting read? Here are my latest suggestions. Everything is awesome! Looking for something thoughtful and uplifting? A great place to start is this recent interview with tech VC Marc Andreessen, who discusses, persuasively, why he is still so optimistic about technology. Particularly useful: Andreessen’s ability to contextualize the evolution of technology, including the... Read More
7
Nov
2022
Delivery of Genetic Medicines: Shehnaaz Suliman on The Long Run
Today’s guest on The Long Run is Shehnaaz Suliman. Shehnaaz is the CEO of Menlo Park, California-based ReCode Therapeutics. Recode is working on lipid nanoparticles to improve the delivery of genetic medicines. These little packages have made it possible to deliver billions of mRNA COVID vaccines in people’s arms, saving millions of lives. It’s been two decades of hard work.... Read More
28
Oct
2022
It Ain’t Over Til It’s Over
If you’re still curious about COVID-19, then good for you. Many people apparently have stopped paying attention, but COVID-19 remains a relevant topic. Here’s where things stand this fall with viral variants and our countermeasures. We are starting a period of the Omicron epidemic in which the numbering is no longer B1, B2, B3, B4, B5. We’re into the Omicron... Read More