27
Oct
2022
Vaxcyte Takes on Pfizer, Novartis Challenges AZ, & Time Gets $100M
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27
Oct
2022
You Have Chosen … Poorly: Why Drug Developers Make Bad Decisions
Drug development remains an incredibly expensive endeavor. Much of the cost can be attributed to late-stage clinical trial failures. The burden is borne first and foremost by clinical trial participants who aren’t helped by the experimental medicine. It also significantly impacts the companies sponsoring these studies. Everyone would like to improve the chances that a novel medicine that advances into... Read More
26
Oct
2022
Single-Cell Analysis for Precision Medicine: Tariq Kassum on The Long Run
Today’s guest on The Long Run is Tariq Kassum. Tariq is the CEO of Cambridge, Mass.-based Celsius Therapeutics. Celsius emerged on the scene in May 2018 with a $65 million Series A led by Third Rock Ventures. It was built on the conviction that single cell analysis will shed light on new targets for the treatment of cancer, autoimmunity and... Read More
26
Oct
2022
Biotech Executives Call for Action on Reproductive Health Rights
Dear Friends and Biopharma colleagues, The rapidly approaching midterm elections carry the potential to dramatically reshape the political landscape in myriad ways. The importance of the US Supreme Court’s Dobbs decision in June, overturning Roe v. Wade, looms large. At this critical time, we must be clear that Dobbs was about more than abortion. With the decision to eliminate a... Read More
26
Oct
2022
Variant Bio Strikes New Pharma Bargain, Shares Benefits of Human Genetic Research
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20
Oct
2022
Bezos Bets on Fred Hutch, Prime Medicine Bucks the Trend, and PacBio Throws Down
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19
Oct
2022
Success Should Be Celebrated. So Should Failure, Done the Right Way
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17
Oct
2022
A Brief History of Oligonucleotide Therapeutics
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14
Oct
2022
Matchpoint Gets $100M to Take Covalent Binders Into Autoimmune Disease
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13
Oct
2022
The Next Pandemic May Be Bacterial or Fungal. What Are We Doing to Prepare?
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12
Oct
2022
Inflation Reduction Act: Big Changes Lurking for Drug Development
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11
Oct
2022
Protein Degraders For Outside the Cell: Aetna Wun Trombley on The Long Run
Today’s guest on The Long Run is Aetna Wun Trombley. Aetna is the CEO of South San Francisco-based Lycia Therapeutics. Many in biotech know about targeted protein degraders. Arvinas and Kymera Therapeutics are a couple of the well-known companies that make these drugs which work to inhibit intracellular proteins. This approach has drawn a lot of excitement because it can... Read More
11
Oct
2022
Neumora Snaps Up $112M to Advance Precision Neuroscience Work Through Clinic
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6
Oct
2022
Nobel for Bertozzi, Red Tree Eyes West Coast, & Doubling Down on Singapore
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6
Oct
2022
The Kilimanjaro Climb to Fight Cancer Is Back
I’m taking another biotech team to the highest peak in Africa. Four years after the first team expedition, the Kilimanjaro Climb to Fight Cancer is back with a new crew of 28 biotech executives and investors. Together, we’re going to push ourselves physically, and raise more than $1 million for research at the Fred Hutch Cancer Center. The expedition is... Read More
6
Oct
2022
Red Tree Debuts With $272M, Zeroing In On West Coast Startups
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29
Sep
2022
Eisai and Biogen Bounce Back, Amylyx Approved, & Illumina’s Big Reveal
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26
Sep
2022
Going Upstream Against Inflammation: Samantha Truex on The Long Run
Today’s guest on The Long Run is Samantha Truex. Samantha is the CEO of Waltham, Mass.-based Upstream Bio. Upstream came out of stealth mode with a $200 million Series A financing in June. It’s a big investment in an antibody aimed at the TSLP receptor. It’s a cytokine – an inflammatory protein – that sits at the top of what... Read More
22
Sep
2022
GSK Lifts Up Spero, AlphaFold Inventors Honored, and a Microbiome Milestone
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22
Sep
2022
Rivus Raises $132M to Harness Mitochondrial Energy to Combat Obesity
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