20
Aug
2021
Giving Back and Experiencing Nature
Sometimes we need to get away from work, and the news, to recharge our batteries. August is traditionally that time of year for me. I just got back from the summit of Mt. Baker (elevation 10,781 ft) in the North Cascades of Washington. It was another successful mountain trip with terrific biotech people – entrepreneur Julia Owens, investor Dan Bradbury,... Read More
16
Aug
2021
Vaccination and the Delta Variant: Four Steps Forward, Two Steps Back
The news is all about Delta, Delta, Delta, for good reason. The variants are forcing us to ask and answer, again, a whole set of uncomfortable questions. Sobering findings of the past few weeks have shaken both the American and scientific psyche. People have had to re-assess their perceptions about the COVID-19 vaccines, and the re-emergence of an epidemic many... Read More
12
Aug
2021
Is EQRx an Existential Threat to the Biopharma Industry?
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9
Aug
2021
Better Cancer Drugs for Kids: Julie Grant and Sam Blackman on The Long Run
Today we have a pair of guests on The Long Run — Julie Grant and Sam Blackman. Julie is a venture capitalist – a general partner at Canaan Partners. Sam is a pediatric oncologist and drug developer. After a routine business meeting, they realized they had something in common. They both believed that the pharmaceutical industry can — and should... Read More
5
Aug
2021
Bayer Snaps Up Vividion, Sanofi Grabs Translate Bio, and RIP: Tachi Yamada
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4
Aug
2021
Tachi Yamada, Physician-Scientist-Biopharma Industry Leader, Dies at 76
Tadataka “Tachi” Yamada, a distinguished physician-scientist who became a biopharmaceutical industry leader and a deeply respected advisor to biotech entrepreneurs, died the morning of Aug. 4. He was 76. Yamada died from a heart attack while exercising at home in Seattle, said his son, Takao. “He was a special person who did things to help people. That was his North... Read More
4
Aug
2021
Sonoma Bio, Engineering T-cell Therapies for Autoimmunity, Nabs $265M Series B
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4
Aug
2021
All Inclusive Medicine Needs More Diverse Genomic Data
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2
Aug
2021
Kidney Companies Taking Pages from Precision Oncology Playbook
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29
Jul
2021
FDA Rejections, Midsummer IPOs & Amgen’s Bispecific Buy
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27
Jul
2021
An Industry that Depends on Diversity Should Defend It
[Editor’s Note: I asked Paul to write in response to a biotech executive who’s marketing a new book that claims diversity and inclusion in business is “the defining scam of our time.”] As CEO of a cell therapy company, I know that the human immune system is a pointillist masterpiece, containing trillions of B and T cells with unique antigen... Read More
26
Jul
2021
Career Arc of a Biotech Leader: Sue Desmond-Hellmann on The Long Run
Today’s guest on The Long Run is Sue Desmond-Hellmann. Sue — and I don’t say this about many people — is a biotech industry legend. Sue is an oncologist and a public health professional by training. She made her name in biopharmaceuticals at Genentech from 1995-2009 — the glory days when it became the world’s most important developer of new... Read More
22
Jul
2021
Biogen’s Bumbling Defense, Delta on the Move, & PacBio’s Power Play
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20
Jul
2021
Why We Need mRNA Vaccines in Africa, and For All Who Are Immunocompromised
The HIV pandemic, and COVID-19 pandemic, are intersecting. The relationship between the two conditions is creating an epidemiological synergy that is starting to translate into additional misery for humankind. If we can better understand this phenomenon, we can think more clearly about how to better protect the most vulnerable populations among us – people with HIV, and millions of others... Read More
20
Jul
2021
Rivus Gets $35M to Alter Mitochondria for T2D, NASH, Heart Failure & More
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19
Jul
2021
Investing at the Nexus of Biology & Technology: Jenny Rooke on The Long Run
Today’s guest on The Long Run is Jenny Rooke. Jenny is the founder and managing partner of San Francisco-based Genoa Ventures. I’ve been wanting to invite Jenny on the podcast for a while. Back in 2018, I profiled her as one of “Nine VCs Who Matter, But You Never Read About.” As I wrote then: “VCs take on lots of... Read More
19
Jul
2021
From Delta…to Omega?
I hope you are all enjoying your summer break with (finally) being able to see friends and family (and fine food NOT from a delivery service). You are? Great! Now let me spoil some of that for you. This pandemic is not over I understand the inclination to consider the pandemic behind us. In large parts of the US /... Read More
15
Jul
2021
Payers Revolt Against Biogen’s Aduhelm, FDA Credibility Crisis, and a Prime Financing
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12
Jul
2021
One-and-Done Gene Editing: A Feature or Flaw?
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8
Jul
2021
Verge Genomics Strikes Deal with Lilly to Validate New Targets for ALS
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