10
Jun
2021
Bright Peak Therapeutics Raises $107M to Advance Cytokine Engineering
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10
Jun
2021
T-cell Diagnostic Tests: COVID-19 Pushed Us, and We Can See Where This Leads
In late February 2020, when it became clear that COVID-19 was spreading around the world, our senior management team at Adaptive Biotechnologies took a gamble. We had a hunch that our ability to evaluate T-cell immunity, combined with advanced bioinformatics, could help the scientific community better understand the novel coronavirus. The entire world, it seemed, was focused on B-cell derived... Read More
3
Jun
2021
Amgen’s KRAS Triumph, Eric Lander in the Saddle, and EQRx Takes Aim at PD-L1
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3
Jun
2021
Stablix, Seeking to Stabilize Instead of Degrade Proteins, Raises $63M
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2
Jun
2021
Spatial Biology Coming Into Focus: Brad Gray on The Long Run
Today’s guest on The Long Run is Brad Gray. Brad is the CEO of Seattle-based NanoString Technologies. NanoString started out in the early 2000s by making digital “bar codes” that allowed it to do multi-plex gene expression – the analysis of multiple genes at once, and the extent to which they were dialled on or off in a given sample.... Read More
1
Jun
2021
Learning from Mistakes in a Pandemic, Aspiring to Make Better Decisions Each Day
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1
Jun
2021
The Promise and Challenge of Deriving Meaningful Clinical Insights From Wearables
Wearable devices have an ability to capture lots of data, in real-time and over long periods of time, that may reflect aspects of an individual person’s health. But (and this is a common theme in the application of data science to healthcare), gathering volumes of data is one thing – deriving meaning from these data in a way that significantly... Read More
27
May
2021
GSK, Vir Win Antibody OK, Sanofi-GSK Moves to Phase III, & a Day One IPO
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27
May
2021
From Fitness To Flourish: Expanding the Scope of Digital Exercise
Sometimes the most relevant digital health companies have the least elaborate technology. More than a decade ago, I discussed UpToDate, a fairly basic medicine e-textbook, served through a web-based app. It was then, and still remains, a go-to site for timely, high-quality medical information relevant to clinicians. There’s nothing fancy about it, it just works. Recently, I discovered a similar... Read More
26
May
2021
11 Asian-American Executives Shaping the Future of Biopharma
The biopharma industry was pressured to get faster and more innovative to respond to the urgent global health challenge of the past year. Asian-American executives have played a key role in leading this charge, although they often aren’t in front of the cameras and microphones. As part of Asian American and Pacific Islander Heritage Month, we wanted to stop and... Read More
20
May
2021
GSK Persists with Vaccines, ASCO Abstracts, & Biogen Gene Therapy Fizzles
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19
May
2021
SQZ Biotech Shortens Cell Therapy Manufacturing Time, Demonstrates Safety
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18
May
2021
Vedere II, After Novartis Acquisition, Snags $77M for Gene Therapy to Restore Vision
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17
May
2021
Singapore: Punching Above its Weight to Become BioNTech’s Regional mRNA Partner
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15
May
2021
Learning From Post-It: Your Solution Is Not My Problem – Except When It is
A frequent – and frequently correct – critique of entrepreneurs bearing technology is “your solution is not my problem.” Healthcare – among many other domains, perhaps all domains – has been beset by “solutionism,” the idea that my clever technology will solve your hideously complex problem. But perhaps it makes no more sense to instinctively reject this mindset as it... Read More
13
May
2021
Pfizer Advances to Adolescents, Xontogeny’s New Fund & Rekindling Curiosity
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12
May
2021
Aducanumab & the Alzheimer’s Moonshot: What Would It Be Worth to Keep Your Mind?
Have you ever met someone with Alzheimer’s disease? Odds are you probably have. Odds are that question calls to mind the face of a beloved grandparent, neighbor, or family friend whom you’ve stopped by to visit, nervously clenching a bouquet of flowers. You greet them hopefully and wonder if they’ll remember you this time. America’s population is aging. About 6.2... Read More
11
May
2021
Appia Bio Seeks Off-the-Shelf Cancer Therapy With Rare iNKT Cells
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6
May
2021
Biden Threatens Patents, Vaccines Shine, & Biogen’s Pricing Predicament
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6
May
2021
Motivating Fitness With Immersive Experience, Rather Than Competition
Many of us first experience exercise as kids playing sports. Think back to the coach yelling at you and your teammates to run the extra lap. Maybe this helps explain why fitness and competition seem inextricably linked to so many adults, so many years later. Digital fitness companies know this. Many digital fitness offerings lean heavily into the competitive aspect,... Read More