20
Feb
2019

The Boston Cancer Summit and SF Cancer Summit. See the Agenda & Get Your Tickets

The Boston Cancer Summit is loaded with a stellar lineup of speakers on Apr. 16.

Same deal with the San Francisco Cancer Summit on Apr. 18.

I’m excited to announce the agendas for these special idea-and-networking forums. Hal Barron of GSK, David Schenkein of GV, Cindy Perettie of Foundation Medicine, and Ira Mellman of Genentech are a few of the outstanding speakers.

All proceeds — from tickets and sponsorships — will go directly to support cancer research at the Fred Hutchinson Cancer Research Center, a world leader. These Cancer Summits are part of the Kilimanjaro Climb to Fight Cancer. This is a philanthropic campaign mobilizing biotech executives and investors from around the country to raise $1 million for cancer research.

When you buy a ticket, you will be getting a superb learning opportunity, a rare networking opportunity, and an opportunity to support more terrific cancer biology to come at Fred Hutch.

Please take a look at the agendas below.

Thanks for your support of cancer research.

The Boston Cancer Summit, Apr. 16

Cancer R&D has never been more promising. Yet pricing and access to this new world of cancer therapy remains thorny. These issues have to be resolved if society is going to reap the benefits of this work. Come hear from some of the leading scientists, entrepreneurs, and investors about how they are thinking about the future. All ticket proceeds go to support basic science research at Fred Hutch.

REGISTER NOW: 1-6 pm, Apr. 16, Alexion Pharmaceuticals, 121 Seaport Blvd, Boston

AGENDA

1 pm Registration

1:30 pm Welcome Remarks. Alexion’s Deaidra Smith & Luke Timmerman

1:35 pm Why I’m Doing Kilimanjaro Climb to Fight Cancer (60 seconds each)

  • Uciane Scarlett, associate, Atlas Venture
  • Katrine Bosley, biotech entrepreneur
  • Praveen Tipirneni, CEO, Morphic Therapeutic

1:40 pm New Ideas for Cancer Treatment (10 minute slide presentations)

  • Simba Gill, Evelo Biosciences (monoclonal microbials for cancer)
  • Karen Akinsanya, chief biomedical scientist, Schrodinger
  • Sanjiv Patel, Relay Therapeutics, (computational drug discovery)
  • Art Krieg, Checkmate Pharmaceuticals (CpG oligonucleotides)
  • Tariq Kassum, Obsidian Therapeutics (tunable T-cell therapies)
  • Leigh Zawel, Cullinan Oncology (portfolio of platforms & mechanisms)

2:50 pm Cancer Investment Landscape. Separating the Hype from the Reality

  • Elliott Sigal, venture partner, NEA
  • Phil Rowlands, head, oncology therapeutic area unit, Takeda 
  • Doug Cole, managing partner, Flagship Pioneering (moderator)

3:20 pm BREAK

3:40 pm Where to Focus the Energy? A View From Pharma

  • Paul Biondi, SVP, business development and strategy, Bristol-Myers Squibb
  • John Reed, EVP, global head of R&D, Sanofi
  • Kate Haviland, Blueprint Medicines (moderator)

4 pm How to Make It Easier for Patients to Get Access to New Therapies?

  • Zoe Barry, CEO, ZappRx
  • Richa Wilson, Genentech/Roche, digital partnerships
  • Simon Kennedy, CEO, TriAxia Health (moderator)

4:30 pm What’s a Fair Way to Pay for All This?

  • Jeff Berkowitz, CEO, Real Endpoints
  • Leora Schiff, principal, Altius Strategy Consulting

5 pm Closing Conversation on the Future for Cancer Care

  • David Schenkein, executive chairman, Agios Pharmaceuticals; general partner GV
  • Mary Lynne Hedley, co-founder and president, Tesaro
  • Cindy Perettie, CEO, Foundation Medicine
  • Deb Palestrant, partner, 5AM Ventures (moderator)

5:30 pm A Word on the Kilimanjaro Climb to Fight Cancer.

  • Luke Timmerman

5:35 pm NETWORKING

6 pm END

Buy Tickets for Boston Cancer Summit

 

The San Francisco Cancer Summit, Apr. 18

Cancer R&D has never been more promising. Yet pricing and access to this new world of cancer therapy remains thorny. These issues have to be resolved if society is going to reap the benefits of this work. Come hear from some of the leading scientists, entrepreneurs, and investors about how they are thinking about the future. All ticket proceeds go to support basic science research at Fred Hutch.

REGISTER NOW: 1-6 pm, Apr. 18, Biocom Bay Area, 1 Tower Place, South San Francisco

AGENDA

1 pm Registration

1:30 pm Welcome. JLABS’ Lesley Stolz & Luke Timmerman

1:35 pm Why I’m Doing Kilimanjaro Climb to Fight Cancer (60 seconds each)

  • Lesley Stolz, head, JLABS Bay Area
  • Bill Newell, CEO, Sutro Biopharma
  • Ken Brunt, VP of customer operations, Veracyte
  • Julia Owens, CEO, Millendo Therapeutics

1:40 pm Why Genentech is Betting Big on Personalized T-cell therapies

  • Ira Mellman, vice president, research oncology, Genentech
  • Harlan Robins, member, Fred Hutch; program head, computational biology; co-founder, Adaptive Biotechnologies
  • Kristina Burow, managing director, ARCH Venture Partners (moderator)

2:00 pm New Ideas for Cancer (10 minutes each)

  • Carolyn Bertozzi, Anne T. and Robert M. Bass Professor of Chemistry at Stanford; Co-Founder, Palleon Pharmaceuticals (targeting glycan sensing checkpoints)
  • Omid Farokhzad, CEO, Seer (proteomics for early cancer detection)
  • Angie You, CEO, Amunix Pharmaceuticals (protein therapeutics)
  • Steve James, CEO, Pionyr Immunotherapeutics (antibodies for immune responses in tumor microenvironment)
  • Daniel Corey, founder and CSO, Cero Therapeutics (engineered T cells to engulf and degrade tumors)
  • Alex Franzusoff, CEO, PACT Pharma (neoantigen personalized cell therapy)
  • Ben Hindson, co-founder and CSO, 10X Genomics (insights from single-cell analysis)

3:10 pm The Future of Cancer Immunotherapy. T-cells, bispecifics, combo targeted therapies, all of the above?

  • David Chang, co-founder and CEO, Allogene Therapeutics
  • Bassil Dahiyat, CEO, Xencor
  • Stanley Riddell, member, Fred Hutch; scientific director, Immunotherapy Integrated Research Center; co-founder, Juno Therapeutics
  • Julia Owens, CEO, Millendo Therapeutics (moderator)

3:30 pm BREAK

3:50 pm Beyond the Science: Regulatory, Commercial and Data Transformations Enabling the Cancer Revolution

  • Amy DuRoss, CEO, Vineti
  • Kristen Hege, Corporate VP, translational development, hematology/oncology, Celgene
  • Nina Kjellson, general partner, Canaan Partners (moderator)

4:30 pm What Will it Take for Molecular Diagnostics Reach Their Potential?

  • Bonnie Anderson, co-founder and CEO, Veracyte
  • Kevin Conroy, CEO, Exact Sciences
  • Lesley Stolz, JLABS Bay Area (moderator)

5 pm Closing Conversation on the Future for Cancer Care

  • Hal Barron, chief scientific officer and president of R&D, GSK
  • Larry Corey, past president of Fred Hutch, co-PI, HIV Vaccine Trials Network; co-founder, Juno Therapeutics
  • Racquel Bracken, vice president, Venrock (moderator)

5:30 pm A Word on the Kilimanjaro Climb to Fight Cancer.

  • Luke Timmerman

5:35 pm NETWORKING

6 pm END

Buy Tickets for SF Cancer Summit

6
Feb
2019

Get Tickets Now: The Cancer Summit Series is Coming to Boston, SF, Seattle

We live in a time of tremendous possibility for cancer R&D.

Checkpoint inhibitors, cell therapies, molecular diagnostics that catch cancer early and can guide effective custom treatment – these fields are brimming with progress. All were considered speculative at best a decade ago. The science has never been more promising. Yet pricing and access to this new world of cancer therapy remains thorny. These issues have to be resolved if society is going to reap the benefits of this work.

Come to a Cancer Summit event near you this spring to hear from leading scientists, entrepreneurs, and investors about how they are thinking about the future.

All ticket proceeds go to the Kilimanjaro Climb to Fight Cancer, a philanthropic campaign to support basic cancer research at Fred Hutch.

See the outstanding speakers for each event:

Boston Cancer Summit confirmed speakers:

  • David Schenkein, executive chairman, Agios Pharmaceuticals
  • Mary Lynne Hedley, co-founder and president, Tesaro
  • Cindy Perettie, CEO, Foundation Medicine
  • Sanjiv Patel, CEO, Relay Therapeutics
  • Garry Menzel, CEO, TCR2 Therapeutics
  • Simba Gill, CEO, Evelo Biosciences
  • Uciane Scarlett, associate, Atlas Venture
  • Katrine Bosley, biotech entrepreneur
  • Praveen Tipirneni, CEO, Morphic Therapeutic
  • Zoe Barry, CEO, ZappRx
  • Phil Rowlands, Head, Oncology Therapeutic Area Unit, Takeda Pharmaceuticals
  • Deborah Palestrant, partner, 5AM Ventures; Head, 4:59
  • Elliott Sigal, venture partner, NEA
  • Leigh Zawel, CSO, small molecules, Cullinan Oncology; executive partner, MPM
  • Luke Timmerman, founder and editor, Timmerman Report

SAVE THE DATE: 1-6 pm, April 16, Alexion Pharmaceuticals, 121 Seaport Blvd., Boston

BUY TICKETS HERE

GET TICKETS FOR THE BOSTON CANCER SUMMIT HERE

NOTE: Last year’s events sold out in advance. Buy your tickets early to reserve a seat.

San Francisco Cancer Summit confirmed Speakers:

  • Carolyn Bertozzi, Anne T. and Robert M. Bass Professor of Chemistry at Stanford University and Co-Founder, Palleon Pharmaceuticals
  • Ira Mellman, vice president, research oncology, Genentech
  • Harlan Robins, member, Fred Hutch; program head, computational biology; co-founder, Adaptive Biotechnologies
  • Stanley Riddell, member, Fred Hutch; scientific director, Immunotherapy Integrated Research Center; co-founder, Juno Therapeutics
  • Bonnie Anderson, co-founder and CEO, Veracyte
  • Nina Kjellson, general partner, Canaan Partners
  • Ben Hindson, co-founder and CSO, 10X Genomics
  • Larry Corey, past president of Fred Hutch, co-PI of the HIV Vaccine Trials Network
  • Lesley Stolz, head, JLABS Bay Area
  • Bill Newell, CEO, Sutro Biopharma
  • Omid Farokhzad, CEO, Seer
  • Angie You, CEO, Amunix Pharmaceuticals
  • Steve James, CEO, Pionyr Immunotherapeutics
  • Bassil Dahiyat, CEO, Xencor
  • Luke Timmerman, founder and editor, Timmerman Report

SAVE THE DATE: 1-6 pm, April 18, Biocom Bay Area, 1 Tower Place, South San Francisco

BUY TICKETS HERE

GET TICKETS FOR THE SAN FRANCISCO CANCER SUMMIT HERE

NOTE: Last year’s events sold out in advance. Buy your tickets early to reserve a seat.

Seattle Cancer Summit confirmed speakers:

  • Gary Gilliland, president and director, Fred Hutch
  • Chad Robins, co-founder and CEO, Adaptive Biotechnologies
  • Steve Harr, co-founder and CEO, Sana Biotechnology
  • Charlotte Hubbert, partner, Gates Foundation Venture Capital
  • Peter Thompson, private equity partner, OrbiMed; co-founder, Silverback Therapeutics
  • Sam Blackman, founder and chief medical officer, Day One Therapeutics
  • Heidi Hagen, co-founder and chief strategy officer, Vineti
  • Bob More, partner, Alta Partners
  • Thong Le, CEO, Accelerator Life Science Partners
  • Clayton Knox, chief operating officer, Mavupharma
  • Kristin Anderson, postdoctoral fellow, Fred Hutch Phil Greenberg Lab, Society for Immunotherapy of Cancer Presidential Award-winning young investigator
  • Racquel Bracken, vice president, Venrock
  • Brad Gray, CEO, NanoString Technologies
  • Tom Daniel, venture partner, ARCH Venture Partners
  • Kelly O’Brien, vice president of philanthropy, Fred Hutch
  • Mark Litton, president and COO, Alpine Immune Sciences
  • Luke Timmerman, founder and editor, Timmerman Report

SAVE THE DATE: 1-5:30 pm, May 10, Fred Hutch, Pelton Auditorium, Seattle

BUY TICKETS HERE

GET TICKETS FOR THE SEATTLE CANCER SUMMIT HERE

NOTE: Last year’s events sold out in advance. Buy your tickets early to reserve a seat.

30
Jan
2019

Finding a Way in Genomic Diagnostics: Bonnie Anderson of Veracyte on The Long Run

Bonnie Anderson is today’s guest on The Long Run.

Bonnie Anderson, CEO, Veracyte

Bonnie is the CEO of Veracyte. It’s a genomic diagnostics company in South San Francisco. The company markets a line of tests for thyroid cancer, lung cancer, and idiopathic pulmonary fibrosis.

Veracyte got started in 2008. Bonnie, as co-founder and CEO, was recruited by Kleiner Perkins Caufield & Byers and a couple other venture firms. The VCs were trying to ride the wave of interest in genomic diagnostics, and wanted to know if a business could be built with unique information from gene expression signatures to guide cancer treatment.

The scientific answers didn’t take long to get. Persuading the medical community and the payer community of the value in the information, and getting them to pay for it? That took a lot longer. This is a familiar story for those who follow genomic diagnostics or precision medicine.

Without a lot of notice, Veracyte has made a lot of progress over the last decade. Revenues were up 34 percent in the third quarter. Test volume climbed 23 percent. The company is getting precariously close to break-even. With three marketed tests gaining adoption from physicians and payers, its market valuation up near a 52-week high, with a respectable $720 million valuation the day of this recording.

Bonnie came to entrepreneurship, and Veracyte, after “retiring” from Beckman Coulter. She learned a lot there about how technologies enable new kinds of biological and medical questions to be asked and answered. As a businessperson, she’s also learned the value of perseverance in getting over the many, many obstacles that make it so difficult to get rewarded for creating new diagnostic tests.

I think listeners will appreciate the perseverance you’ll hear in her voice. 

Now, join me and Bonnie Anderson for The Long Run.

2
Jan
2019

From Merck Fast Track to Computer Chem Frontier: Karen Akinsanya on The Long Run

Today’s guest on The Long Run is Karen Akinsanya.

Karen Akinsanya, chief biomedical scientist, Schrodinger

Karen is the chief biomedical scientist at Schrodinger. The New York-based company is a leader in computational chemistry for drug discovery. The company is privately held, and not a household name. But some wealthy and powerful people know it well. Schrodinger counts Bill Gates and David E. Shaw, the hedge fund billionaire, among its major shareholders. Nimbus Therapeutics and Morphic Therapeutic are a couple of young companies that have made strides with its computer modeling to develop new drugs.

Karen came to Schrodinger in 2018 from Big Pharma – Merck, to be specific. She received her PhD in endocrine physiology at Imperial College London. She worked her way from the lab bench to many different aspects of the pharmaceutical business. She was going places at Merck. But as she puts it, she likes new challenges. Karen is focused now on what Schrodinger can enable – how it can put a dent in the industry’s stubborn problem – the lack of drug R&D productivity.   

Karen is a native of the UK, an immigrant, a Mom, and someone who devotes considerable time and energy to youth science education. She recognizes the importance of role models who can encourage young people to go down paths they might not have known existed. I wish I had asked her more about that work, but it was good to at least hear her philosophy on why she makes time for science education volunteer work. It comes up toward the end of the conversation.

Now, join me and Karen Akinsanya for The Long Run.