14
Feb
2022
Rethinking the Cell Therapy Business: Derrell Porter of Cellevolve on The Long Run
Today’s guest on The Long Run is Derrell Porter. Derrell is the founder and CEO of San Francisco-based Cellevolve. This is a different kind of biotech startup. Most startups are all about the R&D. Traditionally, many haven’t built up commercial capabilities in the early days for one big reason — they don’t have anything to sell. They have tended to... Read More
10
Feb
2022
Biotech’s Future off The Beaten Path
The future of biotech isn’t limited to a few square miles in Cambridge, Mass. and South San Francisco. Biotech is starting to spread its wings in minor league towns. That’s good news. It’s also necessary for the industry to grow and continue to better integrate into the wider world. Let’s look at an example close to my home in Seattle.... Read More
9
Feb
2022
Seismic Gets $101M to Use Machine Learning for Autoimmune Drug Discovery
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3
Feb
2022
The World Waits for Novavax, and an FDA Commissioner
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2
Feb
2022
TR’s 7th Anniversary: Thank You
Timmerman Report is 7 years old today. On Feb. 2, 2015, I rode my bike to the office on a wet Seattle morning and turned on the lights. I thought there was a need for clear, probing, contextual biotech journalism. It was a leap of faith, like any entrepreneurial venture. I couldn’t have predicted 90 percent of what came next.... Read More
1
Feb
2022
Targeting Integrins With Small Molecules: Praveen Tipirneni on The Long Run
Today’s guest on The Long Run is Praveen Tipirneni. Praveen is the CEO of Waltham, Mass.-based Morphic Therapeutic. Morphic Therapeutic is developing oral small molecule drugs aimed at integrin targets. There’s some fascinating biology and computational technology underpinning this work, which I discussed a couple years ago on The Long Run with Morphic scientific founder Tim Springer. Just to review... Read More
31
Jan
2022
Gandeeva Raises $40m For Fast Cryo-EM Enabled Drug Discovery
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27
Jan
2022
A Small Step on Drug Pricing
Mark Cuban, the billionaire-turned-reality TV star, made news this week with the Mark Cuban Cost Plus Drug Company. Cuban has been saying for a while that he wants to stick it to the man. The biopharma man. “I could make a fortune from this,” Cuban told Texas Monthly in September. “But I won’t. I’ve got enough money. I’d rather f—... Read More
27
Jan
2022
Simcha, Backed by SR One, Raises $40m to Inject New Life Into IL-18 for Cancer
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20
Jan
2022
Reflecting on MLK and Science in Society
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20
Jan
2022
ImmPACT Bio, with Bispecific CAR-T Showing Durable CRs, Raises $111m Series B
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13
Jan
2022
The Biogen Debacle Continues
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11
Jan
2022
Antibody Engineering & Company Building: Bassil Dahiyat on The Long Run
Today’s guest on The Long Run is Bassil Dahiyat. Bassil is the CEO of Monrovia, Calif.-based Xencor. He’s been on a true Long Run. Bassil co-founded Xencor in 1997 after getting his PhD in chemistry at Caltech. He’s been through a lot of ups and downs in the biotech markets, and taken the company through a couple big strategic shifts.... Read More
6
Jan
2022
Biotech’s Candle Burns Bright in the Dark
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23
Dec
2021
Pfizer, Merck Get COVID Drugs OK’d, Sanofi Buys Amunix, and a New PCSK9 Contender
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20
Dec
2021
Physician-Scientist-Biotech VC: Vineeta Agarwala on The Long Run
Today’s guest on The Long Run is Vineeta Agarwala. Vineeta is a general partner with Andreesen Horowitz’s bio fund. Vineeta has spent a lot of time on the front lines of an explosion in biological data, and efforts to analyze it to develop better therapeutics, diagnostics and digital health applications. Before coming to A16Z, she worked at GV and Flatiron... Read More
16
Dec
2021
JPM Goes Virtual, Pfizer Acquires Arena, & Arc Reimagines the Scientific Enterprise
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9
Dec
2021
A Missed Opportunity for Grownups
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8
Dec
2021
Newpath Partners Secures $350M for Startups Working on Hard Science Problems
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6
Dec
2021
Targeted Small Molecule Protein Degraders: Nello Mainolfi on The Long Run
Today’s guest on The Long Run is Nello Mainolfi. Nello is the president and CEO of Cambridge, Mass.-based Kymera Therapeutics. Kymera is working on targeted protein degraders. These are orally available small molecule compounds. Many in biopharma are excited about them because they have a clever design that allows them to go after targets that have previously been out of... Read More