26
Jun
2022
Women’s Rights Are Under Attack, and Biotech Can Respond
On Friday night, after the Supreme Court’s decision to overturn Roe vs. Wade, my extended family gathered around my mother’s dining table. We were supposed to be there to celebrate my 18-year-old niece’s graduation from high school. We ended up talking late into the night, discussing the implications of the Court’s majority opinion which will greatly restrict access to safe... Read More
23
Jun
2022
Clinical Trials That Deliver Better Social and Financial Returns
Sometimes doing the right thing requires sacrifice. Other times, the right thing for human health can also be a shrewd business move. That was the intriguing result of a study on the returns sponsors can expect from decentralized trials. The study relied on data from Medable and the Tufts Center for the Study of Drug Development. Results were presented this... Read More
22
Jun
2022
Bringing Precision Medicine to Neuro: Ivana Magovcevic-Liebisch on The Long Run
Today’s guest on The Long Run is Ivana Magovcevic-Liebisch She is the CEO of Cambridge, Mass.-based Vigil Neuroscience. The story starts with Amgen. The big biotech made a strategic decision to get out of neuroscience in 2019. That meant a couple of drug programs targeting TREM2 came up for sale. One is a monoclonal antibody, and the other is a... Read More
21
Jun
2022
Why Kymab Agreed to be Acquired by Sanofi
UK-based Kymab made headlines back in January 2021. Sanofi agreed to acquire the antibody drug developer for $1.1 billion upfront, plus $350 million in potential milestones. The main attraction for Sanofi was KY1005, a monoclonal antibody targeting OX40L, a regulator of the immune system. Five months before the deal, Kymab announced it hit both primary endpoints of a Phase 2a... Read More
16
Jun
2022
Day One Shines, Third Rock Carries On and Vertex/CRISPR Deliver
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15
Jun
2022
Third Rock Raises $1.1B Fund, Sticks With Its Knitting in a Downturn
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14
Jun
2022
Seattle Children’s Invests $45M in Minority Scientists Tackling Pediatric Disease
Many bright young people never get a chance to fulfill their potential as scientists because they never get on the usual scientific career on-ramps. Many young people who get sick struggle because no one had the motivation or the wherewithal to develop new treatments or diagnostics. Seattle Children’s Research Institute sees the problems, and has crafted a major initiative to... Read More
12
Jun
2022
Day One Shrinks Brain Tumors for Kids, Gears Up for First-Line Study
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9
Jun
2022
Daiichi’s Game-Changer, Resilience’s Big Week, and the FTC Scrutinizes PBMs
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7
Jun
2022
Rethinking Biotech Manufacturing: Rahul Singhvi on The Long Run
Today’s guest on The Long Run is Rahul Singhvi. Rahul is the co-founder and CEO of Resilience. The company made a splash in the fall of 2020, when it debuted with an $800 million Series A financing. Bob Nelsen of ARCH Venture Partners led the deal. The company has now raised a couple more rounds that add up to more... Read More
7
Jun
2022
Lessons from the Road: What I Learned from Remix’s Series B
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2
Jun
2022
Out in the Community in 2022
TR subscribers: I’m traveling more, and looking forward to seeing more of you in person. I’ll be at the BIO Convention in San Diego, June 13-15. They have plenty of outdoor patio space overlooking the ocean at the San Diego Convention Center. Let’s chat. While at BIO meeting people and gathering ideas, I’m also moderating a panel on improving diversity,... Read More
2
Jun
2022
Startup Profiles: Upstream Gets $200m for Asthma Antibody; Transition Fetches $50m for Condensate Drug Discovery
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26
May
2022
Managing Through a Hard Time Like No Other
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24
May
2022
Seeking Wellness Through More Data, Less Technology, and Better Habits
It only took a pandemic, but well-being has at last emphatically arrived in the corporate world. Before the pandemic, wellness was often viewed as just another item on the HR benefit menu. Some companies offered limited reimbursement for fitness classes, or subsidized access to select health and wellness apps. But in the turbulent wake of COVID-19, well-being is increasingly viewed... Read More
23
May
2022
Building a New Type of Drug Discovery Engine: Chris Gibson on The Long Run
Today’s guest on The Long Run is Chris Gibson. Chris the co-founder and CEO of Salt Lake City-based Recursion. The company was founded in 2013 when Chris was working in the lab of Dean Li at the University of Utah. The idea at Recursion is to do what it calls “industrialized drug discovery.” It combines some of the common tools... Read More
23
May
2022
Sachi Bioworks: Out of the University, Into Outer Space
When they started their first venture together, Dr. Anushree Chatterjee and Dr. Prashant Nagpal were both leading research labs at the University of Colorado, Boulder. Prashant’s lab focused on nanotechnology and molecular biology: Anushree’s focused on building antibiotics for drug-resistant bacteria. That startup, Praan Biosciences, was founded in 2014 to develop improved genetic sequencing technology. Anushree and Prashant had one... Read More
19
May
2022
A Path Forward for More Biotech Workers
Biotech needs more workers. More people who don’t have PhDs and MDs. The industry is 40 years old, and maturing. More companies are developing commercial products. Someone needs to make these products with precision, and at scale. Given the sophisticated nature of the products (cell therapy, gene therapy, advanced biologics, RNA medicines), the fragile global supply chains, and the importance... Read More
17
May
2022
Remix Gets $70m for Small Molecules to Alter RNA Processing
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12
May
2022
Changing the Balance of Power
Early in my career as a physician, I took care of a woman who died from complications of an abortion procedure. The patient had traveled to the blue state where I practiced, from a red state where she lived that restricted abortion access, to obtain care she couldn’t find or afford at home. She had previously gotten a procedure performed... Read More