29
Jul
2021
FDA Rejections, Midsummer IPOs & Amgen’s Bispecific Buy
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27
Jul
2021
An Industry that Depends on Diversity Should Defend It
[Editor’s Note: I asked Paul to write in response to a biotech executive who’s marketing a new book that claims diversity and inclusion in business is “the defining scam of our time.”] As CEO of a cell therapy company, I know that the human immune system is a pointillist masterpiece, containing trillions of B and T cells with unique antigen... Read More
26
Jul
2021
Career Arc of a Biotech Leader: Sue Desmond-Hellmann on The Long Run
Today’s guest on The Long Run is Sue Desmond-Hellmann. Sue — and I don’t say this about many people — is a biotech industry legend. Sue is an oncologist and a public health professional by training. She made her name in biopharmaceuticals at Genentech from 1995-2009 — the glory days when it became the world’s most important developer of new... Read More
22
Jul
2021
Biogen’s Bumbling Defense, Delta on the Move, & PacBio’s Power Play
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20
Jul
2021
Why We Need mRNA Vaccines in Africa, and For All Who Are Immunocompromised
The HIV pandemic, and COVID-19 pandemic, are intersecting. The relationship between the two conditions is creating an epidemiological synergy that is starting to translate into additional misery for humankind. If we can better understand this phenomenon, we can think more clearly about how to better protect the most vulnerable populations among us – people with HIV, and millions of others... Read More
20
Jul
2021
Rivus Gets $35M to Alter Mitochondria for T2D, NASH, Heart Failure & More
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19
Jul
2021
Investing at the Nexus of Biology & Technology: Jenny Rooke on The Long Run
Today’s guest on The Long Run is Jenny Rooke. Jenny is the founder and managing partner of San Francisco-based Genoa Ventures. I’ve been wanting to invite Jenny on the podcast for a while. Back in 2018, I profiled her as one of “Nine VCs Who Matter, But You Never Read About.” As I wrote then: “VCs take on lots of... Read More
19
Jul
2021
From Delta…to Omega?
I hope you are all enjoying your summer break with (finally) being able to see friends and family (and fine food NOT from a delivery service). You are? Great! Now let me spoil some of that for you. This pandemic is not over I understand the inclination to consider the pandemic behind us. In large parts of the US /... Read More
15
Jul
2021
Payers Revolt Against Biogen’s Aduhelm, FDA Credibility Crisis, and a Prime Financing
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12
Jul
2021
One-and-Done Gene Editing: A Feature or Flaw?
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8
Jul
2021
Verge Genomics Strikes Deal with Lilly to Validate New Targets for ALS
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1
Jul
2021
Biogen’s Perilous Path, Intellia’s In Vivo Milestone, & Holiday Financings
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29
Jun
2021
Immunocompromised People Are Vulnerable to COVID-19. We Owe Them Some Answers
As fully vaccinated citizens in our country and around the globe begin to dip their toes in the waters of a post-vaccination world, there are two groups that deserve greater consideration: immunosuppressed or immunocompromised people. This is not a small group of people. Estimates are that about 6.2 percent of adults ages 18-64 in the US are living with weakened... Read More
29
Jun
2021
Lab Supply Shortages Persist, Slowing Down Everyday Experiments
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24
Jun
2021
Lander Pushes ARPA-H, Lilly Follows Fast in Alzheimer’s, & Wyden Moderates on Price
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24
Jun
2021
The Other Half: Decentralized Research is The Path to All-Inclusive Medicine
More than half of the U.S. population is projected to be “other than non-Hispanic white” by 2045. If the current clinical research process doesn’t adapt to these changing population demographics, the life sciences industry will continue developing drugs and devices that are only shown to work for a select few, leaving out the “other half.” Despite efforts, including those from... Read More
24
Jun
2021
EQRx, Exscientia Team Up to Accelerate R&D for Lower-Priced, Better Drugs
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23
Jun
2021
F-Prime Leads $60M Bet on Adela, Scanning the Methylome for Early Signs of Cancer
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23
Jun
2021
Third Rock-Backed Abata Secures $95M for T-reg Cell Therapy Against MS
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23
Jun
2021
Biopharma’s Racial Justice Work is a Start. But More Needs to Happen
Biopharma leaders have pledged to make their companies more diverse and inclusive. MassBio created an open letter on culture, recruitment, development, sustainability and accountability that has been signed by presidents and CEOs of more than 200 member companies. Large and small companies have described some of their specific efforts in public. Bristol-Myers Squibb aims to double the number of executive... Read More